Quinoline hydrazide/hydrazone derivatives: recent insights on antibacterial activity and mechanism of action
Antibiotics are becoming gradually ineffective due to drug resistance, leading to greater
difficulty in the treatment of infectious diseases. Therefore, the development of new chemical …
difficulty in the treatment of infectious diseases. Therefore, the development of new chemical …
Insights of 8-hydroxyquinolines: A novel target in medicinal chemistry
Hydroxyquinoline (8-HQ) is a significant heterocyclic scaffold in organic and analytical
chemistry because of the properties of chromophore and is used to detect various metal ions …
chemistry because of the properties of chromophore and is used to detect various metal ions …
Hydrazone comprising compounds as promising anti-infective agents: Chemistry and structure-property relationship
Despite the adverse effects of microbial hazards on public health, major pharmaceutical
firms have left the field of anti-infective development and a dramatic reduction in the number …
firms have left the field of anti-infective development and a dramatic reduction in the number …
The inhibitive impact of both kinds of 5-isothiocyanatomethyl-8-hydroxyquinoline derivatives on the corrosion of carbon steel in acidic electrolyte
Two new 8-hydroxyquinoline derivatives namely 1-((8-hydroxyquinolin-5-yl) methyl)-3-
methylthiourea (HQMT) and 5-isothiocyanatomethyl-8-hydroxyquinoline (TCHQ) were …
methylthiourea (HQMT) and 5-isothiocyanatomethyl-8-hydroxyquinoline (TCHQ) were …
Design, synthesis, cytotoxic activities, and molecular docking of chalcone hybrids bearing 8-hydroxyquinoline moiety with dual tubulin/EGFR kinase inhibition
MM Amin, GEDA Abuo-Rahma, MSA Shaykoon… - Bioorganic …, 2023 - Elsevier
The present study established thirteen novel 8-hydroxyquinoline/chalcone hybrids 3a–m of
hopeful anticancer activity. According to NCI screening and MTT assay results, compounds …
hopeful anticancer activity. According to NCI screening and MTT assay results, compounds …
[HTML][HTML] Solution chemical properties and anticancer potential of 8-hydroxyquinoline hydrazones and their oxidovanadium (IV) complexes
We report the synthesis and characterization of a family of benzohydrazones (L n, n= 1–6)
derived from 2-carbaldehyde-8-hydroxyquinoline and benzylhydrazides containing different …
derived from 2-carbaldehyde-8-hydroxyquinoline and benzylhydrazides containing different …
[HTML][HTML] Recent advances in the synthesis and biological activity of 8-hydroxyquinolines
Compounds containing the 8-hydroxyquinoline (8-HQ) 1 nucleus exhibit a wide range of
biological activities, including antimicrobial, anticancer, and antifungal effects. The chemistry …
biological activities, including antimicrobial, anticancer, and antifungal effects. The chemistry …
Cutting edge strategies for screening of novel anti-HIV drug candidates against HIV infection: A concise overview of cell based assays
SY Gaikwad, P Phatak, A Mukherjee - Heliyon, 2023 - cell.com
Abstract The advent of Highly Active Antiretroviral Therapy has majorly contributed towards
reducing the morbidity and mortality associated with HIV infected people, thus improving the …
reducing the morbidity and mortality associated with HIV infected people, thus improving the …
Synthesis, Spectral, Crystal structure, Hirshfeld surface, Computational analysis, and Antimicrobial studies of Ethyl-(E)-4-(2-(2-arylidenehydrazinyl)-2-oxoethyl) …
M Rani, S Jayanthi, S Kabilan… - Journal of Molecular …, 2022 - Elsevier
A new series of ethyl-(E)-4-(2-(2-arylidenehydrazinyl)-2-oxoethyl) piperazine-1-carboxylates
(hydrazones) 4a-4e and 5a-5c were designed and synthesized from 1 …
(hydrazones) 4a-4e and 5a-5c were designed and synthesized from 1 …
Design, synthesis, biological evaluation, and in silico studies of quinoxaline derivatives as potent p38α MAPK inhibitors
A new series of quinoxaline derivatives possessing the hydrazone moiety were designed,
synthesized, and screened for in‐vitro anti‐inflammatory activity by the bovine serum …
synthesized, and screened for in‐vitro anti‐inflammatory activity by the bovine serum …