Polyphenol compounds are natural antioxidants, which are rich in anti-inflammatory and
antioxidant components. They have a wide range of medicinal benefits that are believed to …

Head and neck cancer is a malignant tumour with a high mortality rate characterized by late
diagnosis, high recurrence and metastasis rates, and poor prognosis. Head and neck …

The persistence of cancer cells resistant to therapy remains a major clinical challenge. In
triple-negative breast cancer, resistance to chemotherapy results in the highest recurrence …

Thirty-four years since its discovery, NF-κB remains a transcription factor with great potential
for cancer therapy. However, NF-κB–targeted therapies have yet to find a way to be clinically …

Peritendinous adhesion is a major cause of limb dysfunction and disability in clinical
practice. Numerous studies suggest that activation of nuclear factor-κB (NF-κB) pathway in …

Background Drug resistance is a considerable challenge for chemotherapy in non-small cell
lung cancer (NSCLC). Propofol, a commonly used intravenous anesthetics, has been …

NF-κB transcription factors are major drivers of tumor initiation and progression. NF-κB
signaling is constitutively activated by genetic alterations or environmental signals in many …

Alterations in lipid metabolism, commonly disregarded in the past, have been accepted as a
hallmark for cancer. Exploring cancer therapeutics that interrupt the lipid metabolic pathways …