Lessons from the discovery of mitochondrial fragmentation (fission): a review and update

DB Zorov, IA Vorobjev, VA Popkov, VA Babenko… - Cells, 2019 - mdpi.com
Thirty-five years ago, we described fragmentation of the mitochondrial population in a living
cell into small vesicles (mitochondrial fission). Subsequently, this phenomenon has become …

[BUCH][B] Bildverarbeitung und Objekterkennung

H Süße, E Rodner - 2014 - Springer
Ein Lehrbuch über die Bildverarbeitung zu schreiben ist genauso unmöglich wie ein
Lehrbuch der Mathematik oder Physik herauszugeben. Die Bildverarbeitung ist inzwischen …

Intramitochondrial proteostasis is directly coupled to α-synuclein and amyloid β1-42 pathologies

J Lautenschläger, S Wagner-Valladolid… - Journal of Biological …, 2020 - ASBMB
Mitochondrial dysfunction has long been implicated in the neurodegenerative disorder
Parkinson's disease (PD); however, it is unclear how mitochondrial impairment and α …

Novel computer vision algorithm for the reliable analysis of organelle morphology in whole cell 3D images—A pilot study for the quantitative evaluation of …

J Lautenschläger, C Lautenschläger, V Tadic, H Süße… - Mitochondrion, 2015 - Elsevier
The function of intact organelles, whether mitochondria, Golgi apparatus or endoplasmic
reticulum (ER), relies on their proper morphological organization. It is recognized that …

Quantification of Mitochondrial Morphology in situ

VA Popkov, EY Plotnikov, LD Zorova, IB Pevzner… - Cell and Tissue …, 2017 - Springer
The structural organization of mitochondria reflects their functional status and largely is an
index of cell viability. The indirect parameter to assess the functional state of mitochondria in …

[PDF][PDF] Regularized geometric hulls for bio-medical image segmentation

M Körner, MV Krishna, H Süße… - The Annals of the …, 2015 - pub.inf-cv.uni-jena.de
One of the most important and challenging tasks in bio-medical image analysis is the
localization, identification, and discrimination of salient objects or structures. While to date …

Semi-automatic/user-guided segmentation of mitochondria on transmission electron microscopy images

M Çöçelli - 2015 - open.metu.edu.tr
The purpose of the study is to develop and implement some user-guided/semi-automatic
methods to segment mitochondria on transmission electron microscopy images. Earlier …

[PDF][PDF] Количественные подходы к прижизненному анализу морфологии митохондрий

ВА Попков, ЕЮ Плотников, ЛД Зорова… - Цитология, 2016 - tsitologiya.incras.ru
Структурная организация митохондрий является отражением их функционального
состояния и в значительной мере является показателем жизнеспособности клетки …

Intra-mitochondrial protein degradation alleviates alpha-synuclein seeding and Abeta 42 aggregation

J Lautenschläger, S Wagner-Valladolid, AD Stephens… - bioRxiv, 2019 - biorxiv.org
Mitochondria have long been implicated in Parkinson's disease, ever since the discovery
that inhibitors of the mitochondrial complex I can lead to dopaminergic neuron death. We …

[PDF][PDF] Regularized Geometric Hulls for Nucleus Segmentation in Microscopy Images

W Ortmann - pub.inf-cv.uni-jena.de
As segmentation of cells from microscopy images is a very complex and error-prone task, we
present a new unsupervised and fully-automatic method based on Regularized Geometric …