The gut microbiome, ie, the community of bacteria and other microorganisms living in the
human gut, has been implicated both directly and indirectly (mediating the effects of diet) on …

Interleukin (IL)-4 and IL-13 belong to the T helper 2 (Th2) cytokine family, along with IL-3, IL-
5, and IL-9. These cytokines are key mediators of allergic inflammation. They have important …

Gut microbial dysbiosis is associated with the development of autoimmune disease, but the
mechanisms by which microbial dysbiosis affects the transition from asymptomatic …

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by a failure of
spontaneous resolution of inflammation. Although the pro-inflammatory cytokines and …

Inflammation and its resolution is under-studied in medicine despite being essential for
understanding the development of chronic inflammatory disease. In this review article, we …

Abstract Coronavirus disease 2019 (COVID-19) is an infectious disease, caused by severe
acute respiratory syndrome coronavirus 2, which predominantly affects the lungs and, under …

Numerous rheumatologic autoimmune diseases, among which rheumatoid arthritis, are
chronic inflammatory diseases capable of inducing multiple cumulative articular and extra …

Damaged skin cannot prevent harmful bacteria from invading tissues, causing infected
wounds or even severe tissue damage. In this study, we developed a controlled-release …

Although the control of bone-resorbing osteoclasts through osteocyte-derived RANKL is well
defined, little is known about the regulation of osteoclasts by osteocyte death. Indeed …

There are many causes of inflammatory osteolysis, but regardless of etiology and cellular
contexts, the osteoclast is the bone-degrading cell. Thus, the impact of inflammatory …