The human gut microbiota constitutes a vast and complex community of microorganisms.
The myriad of microorganisms present in the intestinal tract exhibits highly intricate …

Bacterial biofilms represent multicellular communities embedded in a matrix of extracellular
polymeric substances, conveying increased resistance against environmental stress factors …

The activator and composition of the NLRP6 inflammasome remain poorly understood. We
find that lipoteichoic acid (LTA), a molecule produced by Gram-positive bacteria, binds and …

Bacteria interact with fungi in a variety of ways to inhibit fungal growth, while the underlying
mechanisms remain only partially characterized. The plant‐beneficial Bacillus and …

Recent insights into the mechanisms by which Mycobacterium tuberculosis, the etiologic
agent of human tuberculosis, is recognized by cytosolic nucleotide sensors have opened …

The ESX (or Type VII) secretion systems are protein export systems in mycobacteria and
many Gram-positive bacteria that mediate a broad range of functions including virulence …

Bacteria export proteins across membranes using a range of transport machineries. Type VII
secretion systems (T7SSs), originally described in mycobacteria, are now known to be …

Streptococcus gallolyticus subspecies gallolyticus (Sgg) has a strong clinical association
with colorectal cancer (CRC) and actively promotes the development of colon tumors …

The inflammasomes are intracellular multimeric protein complexes consisting of an innate
immune sensor, the adapter protein ASC and the inflammatory caspases-1 and/or-11 and …

Motivation Gram-positive bacteria have developed secretion systems to transport proteins
across their cell wall, a process that plays an important role during host infection. These …