Since the commencement of the novel Coronavirus, the disease has quickly turned into a
worldwide crisis so that there has been growing attention in discovering possible hit …

Simple Summary The segmentation of eukaryotic genomes into discrete linear
chromosomes requires processes to solve several major biological problems, including …

Casein kinase-1 alpha (CK1α) is a multifunctional protein kinase that belongs to the
serine/threonine kinases of the CK1α family. It is involved in various signaling pathways …

Casein kinase 2 (CK2) is a conserved serine/threonine-protein kinase involved in
hematopoietic cell survival, cell cycle control, DNA repair, and other cellular processes. It …

To address coronavirus disease (COVID-19), currently, no effective drug or vaccine is
available. In this regard, molecular modeling approaches are highly useful to discover …

Telomeres are crucial structures that preserve genome stability. Their progressive erosion
over numerous DNA duplications determines the senescence of cells and organisms. As …

The rise and widespread occurrence of bacterial resistance has created an evident need for
novel antibacterial drugs. Filamenting temperature-sensitive mutant Z (FtsZ) is a crucial …

Highlights•Shelterins are underexplored anticancer target.•Molecular structures of the
shelterin's protein complex are continuously delivered.•In silico technology can open new …

Due to the rapid spread of the monkeypox virus and rise in the number of cases, there is an
urgent need for the development of effective drugs against the infection. Serine/threonine …

Rho-associated protein kinase 1 (ROCK1) is a member of the AGC family which plays
crucial roles in inflammatory diseases and cancer progression. Elevated expression of …