Challenges and opportunities for develo** electrochemical biosensors with commercialization potential in the point-of-care diagnostics market

AA Akhlaghi, H Kaur, BR Adhikari… - ECS Sensors Plus, 2024 - iopscience.iop.org
There is a plethora of electrochemical biosensors developed for ultrasensitive detection of
clinically relevant biomarkers. However, many of these systems lose their performance in …

Aptamer-based assembly systems for SARS-CoV-2 detection and therapeutics

Y Dong, J Wang, L Chen, H Chen, S Dang… - Chemical Society …, 2024 - pubs.rsc.org
Nucleic acid aptamers are oligonucleotide chains with molecular recognition properties.
Compared with antibodies, aptamers show advantages given that they are readily produced …

A folding-based electrochemical aptasensor for the single-step detection of the SARS-CoV-2 spike protein

F Curti, S Fortunati, W Knoll, M Giannetto… - … applied materials & …, 2022 - ACS Publications
Efficient and timely testing has taken center stage in the management, control, and
monitoring of the current COVID-19 pandemic. Simple, rapid, cost-effective diagnostics are …

CRISPR-Cas12a-mediated label-free electrochemical aptamer-based sensor for SARS-CoV-2 antigen detection

N Liu, R Liu, J Zhang - Bioelectrochemistry, 2022 - Elsevier
Serological antigen testing has emerged as an important diagnostic paradigm in COVID-19,
but often suffers from potential cross-reactivity. To address this limitation, we herein report a …

Aptasensors for the detection of infectious pathogens: Design strategies and point-of-care testing

XF Chen, X Zhao, Z Yang - Microchimica Acta, 2022 - Springer
The epidemic of infectious diseases caused by contagious pathogens is a life-threatening
hazard to the entire human population worldwide. A timely and accurate diagnosis is the …

Aptamer-conjugated gold nanoparticles and their diagnostic and therapeutic roles in cancer

G Deng, H Zha, H Luo, Y Zhou - Frontiers in Bioengineering and …, 2023 - frontiersin.org
The burden of incidence rate and mortality of cancer is increasing rapidly, and the
development of precise intervention measures for cancer detection and treatment will help …

[HTML][HTML] A review on potential electrochemical point-of-care tests targeting pandemic infectious disease detection: COVID-19 as a reference

GC Biswas, S Choudhury, MM Rabbani, J Das - Chemosensors, 2022 - mdpi.com
Fast and accurate point-of-care testing (POCT) of infectious diseases is crucial for
diminishing the pandemic miseries. To fight the pandemic coronavirus disease 2019 …

Aptamers for SARS‐CoV‐2: Isolation, characterization, and diagnostic and therapeutic developments

R Amini, Z Zhang, J Li, J Gu, JD Brennan… - Analysis & …, 2022 - Wiley Online Library
The SARS‐CoV‐2 virus and COVID‐19 pandemic continue to demand effective diagnostic
and therapeutic solutions. Finding these solutions requires highly functional molecular …

Electrochemical biosensors for SARS-CoV-2 detection: Voltametric or impedimetric transduction?

R Antiochia - Bioelectrochemistry, 2022 - Elsevier
During the COVID-19 pandemic, electrochemical biosensors have shown several
advantages including accuracy, low cost, possibility of miniaturization and portability, which …

A nanobody based ultrasensitive electrochemical biosensor for the detection of soluble CTLA-4–A candidate biomarker for cancer development and progression

N Pandey, M Mandal, D Samanta, G Mukherjee… - Biosensors and …, 2023 - Elsevier
A soluble isoform of cytotoxic T-lymphocyte–associated antigen 4 (CTLA-4) has been found
in the serum of healthy individuals and alterations in its expression level have been linked …