Apoptosis (programmed cell death) and its signals-A review

E Obeng - Brazilian Journal of Biology, 2020 - SciELO Brasil
Apoptosis is a sequential order of cell death occurring regularly to ensure a homeostatic
balance between the rate of cell formation and cell death. However, a misplaced of this …

Synthesis, biological characterization and evaluation of molecular mechanisms of novel copper complexes as anticancer agents

C Acilan, B Cevatemre, Z Adiguzel, D Karakas… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Background To overcome the hurdles of cisplatin, majorly its toxicity and resistance, there
has been extensive search for alternative anti-cancer metal-based compounds. Here, three …

May iron (III) complexes containing phenanthroline derivatives as ligands be prospective anticancer agents?

CP Matos, Z Adiguzel, Y Yildizhan, B Cevatemre… - European Journal of …, 2019 - Elsevier
We report the design, synthesis and biological studies on a group of mixed ligand Fe (III)
complexes as anti-cancer drug candidates, namely their interaction with DNA, cytotoxicity …

Palladium (II) saccharinate complexes with bis (2-pyridylmethyl) amine induce cell death by apoptosis in human breast cancer cells in vitro

F Ari, E Ulukaya, M Sarimahmut, VT Yilmaz - Bioorganic & medicinal …, 2013 - Elsevier
The outcomes of breast cancer patients are still poor although new compounds have
recently been introduced into the clinic. Therefore, novel chemical approaches are required …

Calendula arvensis L. as an anti-cancer agent against breast cancer cell lines

N Abutaha, FA Nasr, AZ Mohammed, AH Semlali… - Molecular biology …, 2019 - Springer
Calendula arvensis L. is used in traditional folk medicine for the treatment of several
diseases. Leaves, stems, and flowers of C. arvensis were extracted using a Soxhlet extractor …

[HTML][HTML] Primula auriculata extracts exert cytotoxic and apoptotic effects against HT-29 human colon adenocarcinoma cells

S Behzad, K Ebrahim, M Mosaddegh… - Iranian journal of …, 2016 - ncbi.nlm.nih.gov
Primula auriculata (Tootia) is one of the most important local medicinal plants in Hamedan
district, Iran. To investigate cytotoxicity and apoptosis induction of crude methanolic extract …

A trans-platinum (II) complex induces apoptosis in cancer stem cells of breast cancer

N Aztopal, D Karakas, B Cevatemre, F Ari… - Bioorganic & Medicinal …, 2017 - Elsevier
Recent accumulating evidence has supported the notion that tumors have hierarchically
organized heterogeneous cell populations and a small subpopulation of cells, termed …

The role of cell cycle progression for the apoptosis of cancer cells induced by palladium (II)-saccharinate complexes of terpyridine

O Kacar, B Cevatemre, I Hatipoglu, N Arda… - Bioorganic & Medicinal …, 2017 - Elsevier
Objectives Palladium complexes are potent and less toxic molecules in comparison to other
metal based agents. Here, we characterized two palladium (II) saccharinate complexes with …

[HTML][HTML] Multimodal nanoparticles as alignment and correlation markers in fluorescence/soft X-ray cryo-microscopy/tomography of nucleoplasmic reticulum and …

C Hagen, S Werner, S Carregal-Romero, AN Malhas… - Ultramicroscopy, 2014 - Elsevier
Correlative fluorescence and soft X-ray cryo-microscopy/tomography on flat sample holders
is perfectly suited to study the uncompromised physiological status of adherent cells at its …

Novel cell-penetrating peptide conjugated proteasome inhibitors: anticancer and antifungal investigations

KD Patel, GH De Zoysa, M Kanamala… - Journal of Medicinal …, 2019 - ACS Publications
Cell-penetrating peptide conjugated peptide aldehydes Tat-A and Tat-B showed low
micromolar anticancer and antifungal activities and synergistic action in combination with …