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Function and therapeutic value of astrocytes in neurological diseases
Astrocytes are abundant glial cells in the central nervous system (CNS) that perform diverse
functions in health and disease. Astrocyte dysfunction is found in numerous diseases …
functions in health and disease. Astrocyte dysfunction is found in numerous diseases …
[HTML][HTML] Behaviorally consequential astrocytic regulation of neural circuits
Astrocytes are a large and diverse population of morphologically complex cells that exist
throughout nervous systems of multiple species. Progress over the last two decades has …
throughout nervous systems of multiple species. Progress over the last two decades has …
Neocortical synaptic engrams for remote contextual memories
While initial encoding of contextual memories involves the strengthening of hippocampal
circuits, these memories progressively mature to stabilized forms in neocortex and become …
circuits, these memories progressively mature to stabilized forms in neocortex and become …
Improved tools to study astrocytes
Astrocytes are a type of glial cell that tile the CNS. They interact with multiple cell types,
including neurons, glial cells and blood vessels, and are involved or implicated in brain …
including neurons, glial cells and blood vessels, and are involved or implicated in brain …
Hippocampal astrocytes modulate anxiety-like behavior
Astrocytes can affect animal behavior by regulating tripartite synaptic transmission, yet their
influence on affective behavior remains largely unclear. Here we showed that hippocampal …
influence on affective behavior remains largely unclear. Here we showed that hippocampal …
Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance
Social hierarchy is established as an outcome of individual social behaviors, such as
dominance behavior during long-term interactions with others. Astrocytes are implicated in …
dominance behavior during long-term interactions with others. Astrocytes are implicated in …
Cortical astrocytes independently regulate sleep depth and duration via separate GPCR pathways
Non-rapid eye movement (NREM) sleep, characterized by slow-wave electrophysiological
activity, underlies several critical functions, including learning and memory. However, NREM …
activity, underlies several critical functions, including learning and memory. However, NREM …
From synapses to circuits, astrocytes regulate behavior
Astrocytes are non-neuronal cells that regulate synapses, neuronal circuits, and behavior.
Astrocytes ensheath neuronal synapses to form the tripartite synapse where astrocytes …
Astrocytes ensheath neuronal synapses to form the tripartite synapse where astrocytes …
Hippocampal astrocytes encode reward location
Astrocytic calcium dynamics has been implicated in the encoding of sensory information,,,–,
and modulation of calcium in astrocytes has been shown to affect behaviour,,,–. However …
and modulation of calcium in astrocytes has been shown to affect behaviour,,,–. However …
The role of astrocyte structural plasticity in regulating neural circuit function and behavior
Brain circuits undergo substantial structural changes during development, driven by the
formation, stabilization, and elimination of synapses. Synaptic connections continue to …
formation, stabilization, and elimination of synapses. Synaptic connections continue to …