Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging

K Jomova, R Raptova, SY Alomar, SH Alwasel… - Archives of …, 2023 - Springer
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

[HTML][HTML] The importance of dietary antioxidants on oxidative stress, meat and milk production, and their preservative aspects in farm animals: Antioxidant action, animal …

EN Ponnampalam, A Kiani, S Santhiravel… - Animals, 2022 - mdpi.com
Simple Summary Oxidative stress occurs within biological systems when free radicals,
classified as reactive oxygen species and reactive nitrogen species, are in excess. The …

Oxidative stress: Concept and some practical aspects

H Sies - Antioxidants, 2020 - mdpi.com
Oxidative stress is defined as “an imbalance between oxidants and antioxidants in favor of
the oxidants, leading to a disruption of redox signaling and control and/or molecular …

Vascular inflammation and oxidative stress: major triggers for cardiovascular disease

S Steven, K Frenis, M Oelze, S Kalinovic… - Oxidative medicine …, 2019 - Wiley Online Library
Cardiovascular disease is a leading cause of death and reduced quality of life, proven by
the latest data of the Global Burden of Disease Study, and is only gaining in prevalence …

Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling

MD Brand - Free Radical Biology and Medicine, 2016 - Elsevier
This review examines the generation of reactive oxygen species by mammalian
mitochondria, and the status of different sites of production in redox signaling and pathology …

Mitochondrial ROS formation in the pathogenesis of diabetic cardiomyopathy

N Kaludercic, F Di Lisa - Frontiers in Cardiovascular Medicine, 2020 - frontiersin.org
Diabetic cardiomyopathy is a result of diabetes-induced changes in the structure and
function of the heart. Hyperglycemia affects multiple pathways in the diabetic heart, but …

[HTML][HTML] Oxidative stress and inflammation in renal and cardiovascular complications of diabetes

A Charlton, J Garzarella, KAM Jandeleit-Dahm, JC Jha - Biology, 2020 - mdpi.com
Simple Summary The progressive nature of type 2 diabetes mellitus (T2DM) leads to micro-
and macro-vascular complications, including renal and cardiovascular disease. These …

[HTML][HTML] European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach… - Redox biology, 2017 - Elsevier
Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

Oxidative stress

H Sies, C Berndt, DP Jones - Annual review of biochemistry, 2017 - annualreviews.org
Oxidative stress is two sided: Whereas excessive oxidant challenge causes damage to
biomolecules, maintenance of a physiological level of oxidant challenge, termed oxidative …

[HTML][HTML] Unlocking the power of NOX2: A comprehensive review on its role in immune regulation

K Bode, M Hauri-Hohl, V Jaquet, H Weyd - Redox biology, 2023 - Elsevier
Reactive oxygen species (ROS) are a family of highly reactive molecules with numerous,
often pleiotropic functions within the cell and the organism. Due to their potential to destroy …