The mechanistic target of rapamycin (mTOR) signaling pathway is a crucial cellular
signaling hub that, like the nervous system itself, integrates internal and external cues to …

Autism spectrum disorder (ASD) represents a heterogeneous group of disorders, which
presents a substantial challenge to diagnosis and treatment. Over the past decade …

Mutations that inactivate negative translation regulators cause autism spectrum disorders
(ASD), which predominantly affect males and exhibit social interaction and communication …

Autism spectrum disorders (ASDs) are highly prevalent neurodevelopmental disorders, but
the underlying pathogenesis remains poorly understood. Recent studies have implicated the …

Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders that include
a variety of forms and clinical phenotypes. This heterogeneity complicates the clinical and …

Syndromic autism spectrum disorders represent a group of childhood neurological
conditions, typically associated with chromosomal abnormalities or mutations in a single …

Hyperconnectivity of neuronal circuits due to increased synaptic protein synthesis is thought
to cause autism spectrum disorders (ASDs). The mammalian target of rapamycin (mTOR) is …

Autism is an etiologically and clinically heterogeneous group of disorders, diagnosed solely
by the complex behavioral phenotype. On the basis of the high-heritability index, geneticists …

Co-occurring medical disorders and associated physiological abnormalities in individuals
with autism spectrum disorder (ASD) may provide insight into causal pathways or underlying …

Objectives: Imbalance between excitation and inhibition and increased excitatory-inhibitory
(EI) ratio is a common mechanism in autism spectrum disorders (ASD) that is responsible for …