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Coumarin–benzimidazole hybrids: A review of developments in medicinal chemistry
Coumarin and benzimidazole are privileged structures in medicinal chemistry and are
widely used in drug discovery and development due to their vast biological properties. The …
widely used in drug discovery and development due to their vast biological properties. The …
First-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumor activity
D Hernández-Romero, S Rosete-Luna… - Coordination Chemistry …, 2021 - Elsevier
Cancer can be defined as an irregular functioning of the cell cycle that results in a
progressive loss of cell differentiation and uncontrolled cell growth. Moreover, despite …
progressive loss of cell differentiation and uncontrolled cell growth. Moreover, despite …
[HTML][HTML] Benzimidazole: A versatile scaffold for drug discovery and beyond–A comprehensive review of synthetic approaches and recent advancements in medicinal …
Heterocyclic compounds are foundational in drug discovery, constituting the core structure of
approximately 80% of pharmaceuticals. Benzimidazole, in particular, emerges as a critical …
approximately 80% of pharmaceuticals. Benzimidazole, in particular, emerges as a critical …
Two sandwich-type uranyl-containing polytungstates catalyze aerobic synthesis of benzimidazoles
YF Liu, QL Hu, XJ Chen, K Li, P Luo, GP Yang - Rare Metals, 2024 - Springer
Diversified synthetic strategies are extremely important for the structural diversity of uranium-
containing polyoxometalates (U-POMs) and their functional expansion. Herein, two …
containing polyoxometalates (U-POMs) and their functional expansion. Herein, two …
Second and third-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumour activity
GV Suárez-Moreno, D Hernández-Romero… - Coordination Chemistry …, 2022 - Elsevier
The application of metal compounds in the medical field dates back to the XVI century with
some isolated reports about the therapeutic importance of metals and their compounds in …
some isolated reports about the therapeutic importance of metals and their compounds in …
Nitrosobenzene‐Enabled Chiral Phosphoric Acid Catalyzed Enantioselective Construction of Atropisomeric N‐Arylbenzimidazoles
QJ An, W **a, WY Ding, HH Liu, SH **ang… - Angewandte …, 2021 - Wiley Online Library
Described herein is an imidazole ring formation strategy for the synthesis of axially chiral N‐
arylbenzimidazoles by means of chiral phosphoric acid catalysis. Two sets of conditions …
arylbenzimidazoles by means of chiral phosphoric acid catalysis. Two sets of conditions …
Recent advance in the development of N-heterocyclic derivatives as anti-SARS-CoV-2 inhibitors: A review
The pandemic caused by COVID-19 hinders everything on earth, including physical and
mental health, daily life and the global economy. Currently, there are no defined drugs and …
mental health, daily life and the global economy. Currently, there are no defined drugs and …
Recent advances in the application of heterogeneous catalysts for the synthesis of benzimidazole derivatives
Benzimidazole derivatives have exhibited marvelous utility due to their widespread
pharmaceutical features, including anti-fungal, anti-viral, anti-bacterial, anti-cancer, anti …
pharmaceutical features, including anti-fungal, anti-viral, anti-bacterial, anti-cancer, anti …
Synthesis, antioxidant and anti-diabetic potential of novel benzimidazole substituted coumarin-3-carboxamides
A series of benzimidazole tethered coumarin-3-carboxamide analogues were synthesised
and screened for their antioxidant potential using DPPH and ABTS assay. And α-amylase …
and screened for their antioxidant potential using DPPH and ABTS assay. And α-amylase …
The nano-based catalyst for the synthesis of benzimidazoles
The properties of benzimidazole and its derivatives have been studied over more than one
hundred years. The benzimidazole ring is an important pharmacophore in modern drug …
hundred years. The benzimidazole ring is an important pharmacophore in modern drug …