Coumarin–benzimidazole hybrids: A review of developments in medicinal chemistry

R Gondru, Y Li, J Banothu - European Journal of Medicinal Chemistry, 2022 - Elsevier
Coumarin and benzimidazole are privileged structures in medicinal chemistry and are
widely used in drug discovery and development due to their vast biological properties. The …

First-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumor activity

D Hernández-Romero, S Rosete-Luna… - Coordination Chemistry …, 2021 - Elsevier
Cancer can be defined as an irregular functioning of the cell cycle that results in a
progressive loss of cell differentiation and uncontrolled cell growth. Moreover, despite …

[HTML][HTML] Benzimidazole: A versatile scaffold for drug discovery and beyond–A comprehensive review of synthetic approaches and recent advancements in medicinal …

ND Mahurkar, ND Gawhale, MN Lokhande, SJ Uke… - Results in …, 2023 - Elsevier
Heterocyclic compounds are foundational in drug discovery, constituting the core structure of
approximately 80% of pharmaceuticals. Benzimidazole, in particular, emerges as a critical …

Two sandwich-type uranyl-containing polytungstates catalyze aerobic synthesis of benzimidazoles

YF Liu, QL Hu, XJ Chen, K Li, P Luo, GP Yang - Rare Metals, 2024 - Springer
Diversified synthetic strategies are extremely important for the structural diversity of uranium-
containing polyoxometalates (U-POMs) and their functional expansion. Herein, two …

Second and third-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumour activity

GV Suárez-Moreno, D Hernández-Romero… - Coordination Chemistry …, 2022 - Elsevier
The application of metal compounds in the medical field dates back to the XVI century with
some isolated reports about the therapeutic importance of metals and their compounds in …

Nitrosobenzene‐Enabled Chiral Phosphoric Acid Catalyzed Enantioselective Construction of Atropisomeric N‐Arylbenzimidazoles

QJ An, W **a, WY Ding, HH Liu, SH **ang… - Angewandte …, 2021 - Wiley Online Library
Described herein is an imidazole ring formation strategy for the synthesis of axially chiral N‐
arylbenzimidazoles by means of chiral phosphoric acid catalysis. Two sets of conditions …

Recent advance in the development of N-heterocyclic derivatives as anti-SARS-CoV-2 inhibitors: A review

W Ettahiri, M Adardour, S Alaoui, AEA Allah… - Phytochemistry …, 2024 - Elsevier
The pandemic caused by COVID-19 hinders everything on earth, including physical and
mental health, daily life and the global economy. Currently, there are no defined drugs and …

Recent advances in the application of heterogeneous catalysts for the synthesis of benzimidazole derivatives

M Mavvaji, S Akkoc - Coordination Chemistry Reviews, 2024 - Elsevier
Benzimidazole derivatives have exhibited marvelous utility due to their widespread
pharmaceutical features, including anti-fungal, anti-viral, anti-bacterial, anti-cancer, anti …

Synthesis, antioxidant and anti-diabetic potential of novel benzimidazole substituted coumarin-3-carboxamides

DN Patagar, SR Batakurki, R Kusanur, SM Patra… - Journal of Molecular …, 2023 - Elsevier
A series of benzimidazole tethered coumarin-3-carboxamide analogues were synthesised
and screened for their antioxidant potential using DPPH and ABTS assay. And α-amylase …

The nano-based catalyst for the synthesis of benzimidazoles

RS Keri, V Adimule, P Kendrekar, BS Sasidhar - Topics in Catalysis, 2022 - Springer
The properties of benzimidazole and its derivatives have been studied over more than one
hundred years. The benzimidazole ring is an important pharmacophore in modern drug …