Transcription regulation networks control the expression of genes. The transcription
networks of well-studied microorganisms appear to be made up of a small set of recurring …

Quorum sensing is a cell-cell communication process in which bacteria use the production
and detection of extracellular chemicals called autoinducers to monitor cell population …

Gene expression is a multistep process that involves the transcription, translation and
turnover of messenger RNAs and proteins. Although it is one of the most fundamental …

The transcription factors OCT4, SOX2, and NANOG have essential roles in early
development and are required for the propagation of undifferentiated embryonic stem (ES) …

Praise for the first edition:… superb, beautifully written and organized work that takes an
engineering approach to systems biology. Alon provides nicely written appendices to …

Engineered systems are often built of recurring circuit modules that carry out key functions.
Transcription networks that regulate the responses of living cells were recently found to obey …

Much of a cell's activity is organized as a network of interacting modules: sets of genes
coregulated to respond to different conditions. We present a probabilistic method for …

At publication, The Control Handbook immediately became the definitive resource that
engineers working with modern control systems required. Among its many accolades, that …

Complex biological, technological, and sociological networks can be of very different sizes
and connectivities, making it difficult to compare their structures. Here we present an …

Proteins, nucleic acids, and small molecules form a dense network of molecular interactions
in a cell. Molecules are nodes of this network, and the interactions between them are edges …