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[HTML][HTML] miRNA: a promising therapeutic target in cancer
microRNAs are small non-coding RNAs that regulate several genes post-transcriptionally by
complementarity pairing. Since discovery, they have been reported to be involved in a …
complementarity pairing. Since discovery, they have been reported to be involved in a …
miRNAs: potential as biomarkers and therapeutic targets for cancer
MicroRNAs (miRNAs) are single-stranded, non-coding RNA molecules that regulate gene
expression post-transcriptionally by binding to messenger RNAs. miRNAs are important …
expression post-transcriptionally by binding to messenger RNAs. miRNAs are important …
EMT factors and metabolic pathways in cancer
The epithelial-mesenchymal transition (EMT) represents a biological program during which
epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is …
epithelial cells lose their cell identity and acquire a mesenchymal phenotype. EMT is …
M2 macrophage-derived exosomes promote cell migration and invasion in colon cancer
J Lan, LI Sun, F Xu, L Liu, F Hu, D Song, Z Hou… - Cancer …, 2019 - aacrjournals.org
Clinical and experimental evidence has shown that tumor-associated macrophages promote
cancer initiation and progression. However, the macrophage-derived molecular …
cancer initiation and progression. However, the macrophage-derived molecular …
The role of microRNA-21 (miR-21) in pathogenesis, diagnosis, and prognosis of gastrointestinal cancers: A review
MicroRNAs (miRNAs) are small non-coding RNAs regulating the expression of several
target genes. miRNAs play a significant role in cancer biology, as they can downregulate …
target genes. miRNAs play a significant role in cancer biology, as they can downregulate …
Classical and noncanonical functions of miRNAs in cancers
Alterations in microRNAs (miRNAs) expression are causative in the initiation and
progression of human cancers. The molecular events responsible for the widespread …
progression of human cancers. The molecular events responsible for the widespread …
Emerging role of non‐coding RNA in health and disease
Human diseases have always been a significant turf of concern since the origin of mankind.
It is cardinal to know the cause, treatment, and cure for every disease condition. With the …
It is cardinal to know the cause, treatment, and cure for every disease condition. With the …
Immune cells-derived exosomes function as a double-edged sword: role in disease progression and their therapeutic applications
Exosomes, ranging in size from 30 to 150 nm as identified initially via electron microscopy in
1946, are one of the extracellular vesicles (EVs) produced by many cells and have been the …
1946, are one of the extracellular vesicles (EVs) produced by many cells and have been the …
[HTML][HTML] From molecular mechanisms to therapeutics: understanding MicroRNA-21 in cancer
J Rhim, W Baek, Y Seo, JH Kim - Cells, 2022 - mdpi.com
MicroRNAs (miRNAs) are small noncoding RNAs that play an important role in regulating
gene expression at a posttranscriptional level. As one of the first discovered oncogenic …
gene expression at a posttranscriptional level. As one of the first discovered oncogenic …
Epigenetic regulation in hematopoiesis and its implications in the targeted therapy of hematologic malignancies
A Zhao, H Zhou, J Yang, M Li, T Niu - Signal transduction and targeted …, 2023 - nature.com
Hematologic malignancies are one of the most common cancers, and the incidence has
been rising in recent decades. The clinical and molecular features of hematologic …
been rising in recent decades. The clinical and molecular features of hematologic …