Centrifugal-assisted sample preparation techniques: Innovations and applications in bioanalysis

C Suwanvecho, LK Krčmová, F Švec - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Sample preparation is a critical and resource-intensive phase of bioanalysis. The centrifuge
is the most commonly used equipment in clinical research and practice for isolating cells …

In-depth analysis of biocatalysts by microfluidics: An emerging source of data for machine learning

M Vasina, D Kovar, J Damborsky, Y Ding, T Yang… - Biotechnology …, 2023 - Elsevier
Nowadays, the vastly increasing demand for novel biotechnological products is supported
by the continuous development of biocatalytic applications that provide sustainable green …

A capillary-based microfluidic chip with the merits of low cost and easy fabrication for the rapid detection of acute myocardial infarction

X Li, C Xu, H Chen, F Yi, J Liao, J Han, C Li, W Han… - Talanta, 2023 - Elsevier
Point-of-care testing methods currently utilize rapid, portable, inexpensive, and multiplexed
on-site detection. Microfluidic chips have become a very promising platform with broad …

Artificial intelligence-controlled microfluidic device for fluid automation and bubble removal of immunoassay operated by a smartphone

NH Bhuiyan, JH Hong, MJ Uddin, JS Shim - Analytical Chemistry, 2022 - ACS Publications
There have been tremendous innovations in microfluidic clinical diagnostics to facilitate
novel point-of-care testing (POCT) over the past decades. However, the automatic operation …

On-Line Dual-Active Valves Based Centrifugal Microfluidic Chip for Fully Automated Point-of-Care Immunoassay

C Qian, C Wan, S Li, Y **ao, H Yuan, S Gao… - Analytical …, 2023 - ACS Publications
There remains an unmet need for a fully integrated microfluidic platform that can
automatically perform multistep and multireagent immunoassays. Here, we proposed a …

Recent progress in CRISPR-based microfluidic assays and applications

P Li, H **ong, B Yang, X Jiang, J Kong… - TrAC Trends in Analytical …, 2022 - Elsevier
In the past few years, CRISPR-based (Clustered regularly interspaced short palindromic
repeats-based) detection techniques have arisen in the field of bioanalysis, molecular …

Integrated microfluidic devices for in vitro diagnostics at point of care

D Liu, Y Wang, X Li, M Li, Q Wu, Y Song, Z Zhu… - …, 2022 - Wiley Online Library
Given the continuous and growing demand for point of care (POC) diagnostic tests, attention
has been shifted toward integration and miniaturization of laboratory protocols into “sample …

Biotechnological advancements towards water, food and medical healthcare: A review

A Soozanipour, F Ejeian, Y Boroumand, A Rezayat… - Chemosphere, 2023 - Elsevier
The global health status is highly affected by the growing pace of urbanization, new
lifestyles, climate changes, and resource exploitation. Modern technologies pave a …

Application of microfluidic technology in antibody screening

H Sun, N Hu, J Wang - Biotechnology Journal, 2022 - Wiley Online Library
Specific antibodies are widely used in the biomedical field. Current screening methods for
specific antibodies mainly involve hybridoma technology and antibody engineering …

Digital process control of multi-step assays on centrifugal platforms using high-low-high rotational-pulse triggered valving

PL Early, NA Kilcawley, NA McArdle, M Renou… - Plos one, 2023 - journals.plos.org
Due to their capability for comprehensive sample-to-answer automation, the interest in
centrifugal microfluidic systems has greatly increased in industry and academia over the last …