Metadynamics Study of Lipid-Mediated Antibacterial Toxin Binding to the EmrE Multiefflux Protein

J Bodosa, JB Klauda - The Journal of Physical Chemistry B, 2024‏ - ACS Publications
EmrE is a bacterial efflux protein in the small multidrug-resistant (SMR) family present in
Escherichia coli. Due to its small size, 110 residues in each dimer subunit, it is an ideal …

The C-terminus of the multi-drug efflux pump EmrE prevents proton leak by gating transport

M Brousseau, D Teng, NE Thomas, GA Voth… - bioRxiv, 2024‏ - biorxiv.org
The model multi-drug efflux pump from Escherichia coli, EmrE, can perform multiple types of
transport leading to different biological outcomes, conferring resistance to some drug …