Background Ever since a lung cancer epidemic emerged in the mid-1900s, the
epidemiology of lung cancer has been intensively investigated to characterize its causes …

A new non-invasive and potentially inexpensive frontier in the diagnosis of cancer relies on
the detection of volatile organic compounds (VOCs) in exhaled breath samples. Breath can …

Lung cancer (LC) is the leading cause of cancer mortality, with more than 1 million deaths
worldwide every year. 1, 2 There are two major forms of LC disease: nonsmall cell LC …

Using biomarkers to select the most at-risk population, to detect the disease while
measurable and yet not clinically apparent has been the goal of many investigations. Recent …

Lung cancer is the leading cause of cancer death. Results of therapeutic interventions are
particularly discouraging when the disease is discovered in an advanced stage. Early …

The synthesis of acute-phase protein serum amyloid A (SAA) is largely regulated by
inflammation-associated cytokines and a high concentration of circulating SAA may …

Each year, millions of pulmonary nodules are discovered by computed tomography and
subsequently biopsied. Because most of these nodules are benign, many patients undergo …

Background Lung cancer is the leading cause of cancer deaths worldwide. New diagnostics
are needed to detect early stage lung cancer because it may be cured with surgery …

Abstract Development of noninvasive, reliable biomarkers for lung cancer diagnosis has
many clinical benefits knowing that most of lung cancer patients are diagnosed at the late …

Abstract Objectives “PAULA's” test (P rotein A ssays U tilizing L ung cancer A nalytes) is a
novel multiplex immunoassay blood test that incorporates both tumor antigens and …