Availability of artificial light and light-emitting devices have altered human temporal life,
allowing 24-hour healthcare, commerce and production, and expanding social life around …

Circadian clocks are endogenous oscillators that control 24-hour physiological and
behavioural processes in organisms. These cell-autonomous clocks are composed of a …

Circadian clocks are endogenous oscillators that control 24-h physiological and behavioral
processes. The central circadian clock exerts control over myriad aspects of mammalian …

The intestinal microbiota undergoes diurnal compositional and functional oscillations that
affect metabolic homeostasis, but the mechanisms by which the rhythmic microbiota …

Disrupted sleep-wake and molecular circadian rhythms are a feature of aging associated
with metabolic disease and reduced levels of NAD+, yet whether changes in nucleotide …

Mammalian physiology exhibits 24-hour cyclicity due to circadian rhythms of gene
expression controlled by transcription factors that constitute molecular clocks. Core clock …

The mammalian circadian clock relies on the transcription factor CLOCK: BMAL1 to
coordinate the rhythmic expression of 15% of the transcriptome and control the daily …

Circadian timekee** allows appropriate temporal regulation of an organism's internal
metabolism to anticipate and respond to recurrent daily changes in the environment …

Epigenetics has enriched human disease studies by adding new interpretations to disease
features that cannot be explained by genetic and environmental factors. However …

All biological processes, living organisms, and ecosystems have evolved with the Sun that
confers a 24-hour periodicity to life on Earth. Circadian rhythms arose from evolutionary …