Molecular biology of colorectal cancer

R Gryfe, B Bapat, S Gallinger, C Swallow… - Current problems in …, 1997 - Elsevier
Colorectal cancer is a significant cause of morbidity and mortality in Western populations.
This cancer develops as a result of the pathologic transformation of normal colonic …

Combined hyperthermia and radiotherapy for the treatment of cancer

P Kaur, MD Hurwitz, S Krishnan, A Asea - Cancers, 2011 - mdpi.com
Radiotherapy is used to treat approximately 50% of all cancer patients, with varying success.
Radiation therapy has become an integral part of modern treatment strategies for many …

[PDF][PDF] Expression profiling in multistage hepatocarcinogenesis: identification of HSP70 as a molecular marker of early hepatocellular carcinoma

M Chuma, M Sakamoto, K Yamazaki, T Ohta… - …, 2003 - Wiley Online Library
Hepatocellular carcinoma (HCC) associated with chronic liver disease evolves from
precancerous lesions and early HCC to a progressed form. Nodule‐in‐nodule–type HCC …

Prognostic value of the CD4+/CD8+ ratio of tumour infiltrating lymphocytes in colorectal cancer and HLA-DR expression on tumour cells

ACP Diederichsen, J v B Hjelmborg… - Cancer Immunology …, 2003 - Springer
The purpose of this study was to clarify whether HLA-DR expression of colorectal tumour
cells or the CD4+/CD8+ ratio of the tumour infiltrating lymphocytes is significantly associated …

COVID-19. Pandemic surgery guidance

BLDM Brücher, G Nigri, A Tinelli, J Florencio… - 4 OPEN, 2020 - iris.uniroma1.it
Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …

HLA class II antigen-processing pathway in tumors: molecular defects and clinical relevance

B Seliger, M Kloor, S Ferrone - Oncoimmunology, 2017 - Taylor & Francis
The human leukocyte antigen (HLA) class II antigen-processing machinery (APM) presents
to cognate CD4+ T-cells antigenic peptides mainly generated from exogeneous proteins in …

Heat shock proteins HSPA1 and HSP90AA1 are upregulated in colorectal polyps and can be targeted in cancer cells by anti-inflammatory oxicams with arylpiperazine …

I Szczuka, J Wierzbicki, P Serek, BM Szczęśniak-Sięga… - Biomolecules, 2021 - mdpi.com
Heat shock proteins HSPA1/Hsp70α and HSP90AA1/Hsp90α are crucial for cancer growth
but their expression pattern in colorectal polyps or whether they can be modulated by …

60KDa chaperonin (HSP60) is over-expressed during colorectal carcinogenesis

F Cappello, M Bellafiore, A Palma, S David… - European Journal of …, 2003 - ejh.it
The aim of the present study was to evaluate the expression of the heat shock protein 60
(HSP60), a mitochondrial matrix-associated protein belonging to the chaperonin family, in …

Proteomic profiling of heat shock protein 70 family members as biomarkers for hepatitis C virus‐related hepatocellular carcinoma

M Takashima, Y Kuramitsu, Y Yokoyama, N Iizuka… - …, 2003 - Wiley Online Library
To identify proteins linked to the pathogenesis of hepatocellular carcinoma (HCC)
associated with hepatitis C virus (HCV), we profiled protein expression levels in samples of …

Prognostic significance of heat shock proteins 27 and 70 in patients with squamous cell carcinoma of the esophagus

K Kawanishi, H Shiozaki, Y Doki, I Sakita… - … Journal of the …, 1999 - Wiley Online Library
BACKGROUND Heat shock proteins (HSPs) first were defined as proteins induced by heat
shock and other environmental and pathophysiologic stresses and are implicated in protein …