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Hormonal regulation of c-KIT receptor and its ligand: implications for human infertility?
The c-KIT, a tyrosine kinase receptor, and its ligand the stem cell factor (SCF) play an
important role in the production of male and female gametes. The interaction of SCF with c …
important role in the production of male and female gametes. The interaction of SCF with c …
Activin bioactivity affects germ cell differentiation in the postnatal mouse testis in vivo
The transforming growth factor beta superfamily ligand activin A controls juvenile testis
growth by stimulating Sertoli cell proliferation. Testicular levels are highest in the first …
growth by stimulating Sertoli cell proliferation. Testicular levels are highest in the first …
Seminal level of clusterin in infertile men as a significant biomarker reflecting spermatogenesis
T Fukuda, H Miyake, N Enatsu, K Matsushita… - Andrologia, 2016 - Wiley Online Library
The objective of this study was to assess the impact of seminal clusterin level on
spermatogenesis in infertile men. This study included 89 men who visited our clinic due to …
spermatogenesis in infertile men. This study included 89 men who visited our clinic due to …
Effects of a mixture of low doses of atrazine and benzo [a] pyrene on the rat seminiferous epithelium either during or after the establishment of the blood-testis barrier …
P Durand, A Blondet, G Martin, D Carette, G Pointis… - Toxicology in Vitro, 2020 - Elsevier
Atrazine (ATZ), a widely used agricultural pesticide and benzo [a] pyrene (BaP), a ubiquitous
environmental human carcinogen can induce alterations of spermatogenesis. In the present …
environmental human carcinogen can induce alterations of spermatogenesis. In the present …
Effects of low doses of carbendazim or iprodione either separately or in mixture on the pubertal rat seminiferous epithelium: An ex vivo study
It has been shown that non-cytotoxic doses of Carbendazim (CBZ), a broad-spectrum
benzimidazole fungicide, possess endocrine-disrupting (androgen-like) actions, ex vivo, on …
benzimidazole fungicide, possess endocrine-disrupting (androgen-like) actions, ex vivo, on …
The reproductive activity in the testis of Podarcis s. sicula involves D-aspartic acid: a study on c-kit receptor protein, tyrosine kinase activity and PCNA protein during …
The current study provides substantial evidence that the pattern of synthesis of d-aspartic
acid (d-Asp) in the testes of lizard Podarcis s. sicula throughout the reproductive cycle is in …
acid (d-Asp) in the testes of lizard Podarcis s. sicula throughout the reproductive cycle is in …
Decrease of both stem cell factor and clusterin mRNA levels in testicular biopsies of azoospermic patients with constitutive or idiopathic but not acquired …
BACKGROUND: Sertoli cells nurse germ cells during spermatogenesis, and alterations of
Sertoli cell functions have been suggested in cases of spermatogenic failures. METHODS: In …
Sertoli cell functions have been suggested in cases of spermatogenic failures. METHODS: In …
Low concentrations of glyphosate alone affect the pubertal male rat meiotic step: An in vitro study
B Antonine, M Guillaume, D Philippe, P Marie-Hélène - Toxicology in Vitro, 2022 - Elsevier
Glyphosate is the most used herbicide in the world. Controversial studies exist on its effect
on the male reproductive system. We used the validated BioAlter® model to test the effects …
on the male reproductive system. We used the validated BioAlter® model to test the effects …
Clusterin produced by S ertoli cells inhibits heat stress‐induced apoptosis in the rat testis
K Matsushita, H Miyake, K Chiba, M Fujisawa - Andrologia, 2016 - Wiley Online Library
The objectives of this study were to determine whether the inhibition of clusterin expression
in rat Sertoli cells enhances heat stress‐induced apoptosis. The scrotums of rats were …
in rat Sertoli cells enhances heat stress‐induced apoptosis. The scrotums of rats were …
Hyperhomocysteinemia inhibited cardiac stem cell homing into the peri-infarcted area post myocardial infarction in rats
BACKGROUND: Hyperhomocysteinemia (HHcy) has been reported as an independent risk
factor for coronary artery disease; however it is not clear regarding the action of HHcy on the …
factor for coronary artery disease; however it is not clear regarding the action of HHcy on the …