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[HTML][HTML] STING as an emerging therapeutic target for drug discovery: Perspectives from the global patent landscape
Abstract Background The STimulator of INterferon Genes (STING) plays an essential role in
the innate immune system by inducing the expression of type I interferons (IFNs) and …
the innate immune system by inducing the expression of type I interferons (IFNs) and …
Harnessing cGAS‐STING pathway for cancer immunotherapy: from bench to clinic
Recent advances in cancer immunotherapy have accomplished clinical successes in certain
cancer models over the past decade. However, cancer treatments with adoptive cell transfer …
cancer models over the past decade. However, cancer treatments with adoptive cell transfer …
[HTML][HTML] Microbubble-Protected Oncolytic Virotherapy Targeted by Sonoporation Induces Tumor Necrosis and T-Lymphocyte Infiltration in Humanized Mice Bearing …
Oncolytic virotherapy has shown great promise in mediating targeted tumor destruction
through tumor-selective replication and induction of anti-tumor immunity; however, obstacles …
through tumor-selective replication and induction of anti-tumor immunity; however, obstacles …
A 3D printable perfused hydrogel vascular model to assay ultrasound-induced permeability
MK Royse, AK Means, GA Calderon… - Biomaterials …, 2022 - pubs.rsc.org
The development of an in vitro model to study vascular permeability is vital for clinical
applications such as the targeted delivery of therapeutics. This work demonstrates the use of …
applications such as the targeted delivery of therapeutics. This work demonstrates the use of …