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Monkeypox: disease epidemiology, host immunity and clinical interventions
Monkeypox virus (MPXV), which causes disease in humans, has for many years been
restricted to the African continent, with only a handful of sporadic cases in other parts of the …
restricted to the African continent, with only a handful of sporadic cases in other parts of the …
Mpox (formerly monkeypox): Pathogenesis, prevention and treatment
J Lu, H ** vaccines in the era of genomics
The sequence of microbial genomes made all potential antigens of each pathogen available
for vaccine development. This increased by orders of magnitude potential vaccine targets in …
for vaccine development. This increased by orders of magnitude potential vaccine targets in …
The CD83 molecule–an important immune checkpoint
L Grosche, I Knippertz, C König, D Royzman… - Frontiers in …, 2020 - frontiersin.org
The CD83 molecule has been identified to be expressed on numerous activated immune
cells, including B and T lymphocytes, monocytes, dendritic cells, microglia, and neutrophils …
cells, including B and T lymphocytes, monocytes, dendritic cells, microglia, and neutrophils …
Poxvirus tropism
G McFadden - Nature Reviews Microbiology, 2005 - nature.com
Despite the success of the WHO-led smallpox eradication programme a quarter of a century
ago, there remains considerable fear that variola virus, or other related pathogenic …
ago, there remains considerable fear that variola virus, or other related pathogenic …
Cross-presentation in viral immunity and self-tolerance
WR Heath, FR Carbone - Nature Reviews Immunology, 2001 - nature.com
T lymphocytes recognize peptide antigens presented by class I and class II molecules
encoded by the major histocompatibility complex (MHC). Classical antigen-presentation …
encoded by the major histocompatibility complex (MHC). Classical antigen-presentation …
Smallpox vaccines: targets of protective immunity
B Moss - Immunological reviews, 2011 - Wiley Online Library
The eradication of smallpox, one of the great triumphs of medicine, was accomplished
through the prophylactic administration of live vaccinia virus, a comparatively benign relative …
through the prophylactic administration of live vaccinia virus, a comparatively benign relative …
Toll-like receptor ligands directly promote activated CD4+ T cell survival
AE Gelman, J Zhang, Y Choi… - The Journal of Immunology, 2004 - journals.aai.org
Toll-like receptor (TLR) engagement by pathogen-associated molecular patterns (PAMPs) is
an important mechanism for optimal cellular immune responses. APC TLR engagement …
an important mechanism for optimal cellular immune responses. APC TLR engagement …