Reference genes in real-time PCR

B Kozera, M Rapacz - Journal of applied genetics, 2013 - Springer
This paper aims to discuss various aspects of the use of reference genes in qPCR technique
used in the thousands of present studies. Most frequently, these are housekee** genes …

Normalization of qRT-PCR data: the necessity of adopting a systematic, experimental conditions-specific, validation of references

S Guenin, M Mauriat, J Pelloux… - Journal of …, 2009 - academic.oup.com
Quantitative RT-PCR (reverse transcription polymerase chain reaction, also known as qRT-
PCR or real-time RT-PCR) has been used in large proportions of transcriptome analyses …

Quantification of mRNA using real-time RT-PCR

T Nolan, RE Hands, SA Bustin - Nature protocols, 2006 - nature.com
The real-time reverse transcription polymerase chain reaction (RT-qPCR) addresses the
evident requirement for quantitative data analysis in molecular medicine, biotechnology …

Selection of internal control genes for quantitative real-time RT-PCR studies during tomato development process

M Expósito-Rodríguez, AA Borges, A Borges-Pérez… - BMC plant biology, 2008 - Springer
Background The elucidation of gene expression patterns leads to a better understanding of
biological processes. Real-time quantitative RT-PCR has become the standard method for …

An optimized grapevine RNA isolation procedure and statistical determination of reference genes for real-time RT-PCR during berry development

KE Reid, N Olsson, J Schlosser, F Peng, ST Lund - BMC plant biology, 2006 - Springer
Background Accuracy in quantitative real-time RT-PCR is dependent on high quality RNA,
consistent cDNA synthesis, and validated stable reference genes for data normalization …

Selection of reliable reference genes for gene expression studies in peach using real-time PCR

Z Tong, Z Gao, F Wang, J Zhou, Z Zhang - BMC molecular biology, 2009 - Springer
Background RT-qPCR is a preferred method for rapid and reliable quantification of gene
expression studies. Appropriate application of RT-qPCR in such studies requires the use of …

Characterization of housekee** genes in zebrafish: male-female differences and effects of tissue type, developmental stage and chemical treatment

AT McCurley, GV Callard - BMC molecular biology, 2008 - Springer
Background Research using the zebrafish model has experienced a rapid growth in recent
years. Although real-time reverse transcription PCR (QPCR), normalized to an internal …

Super-resolution microscopy reveals ultra-low CD19 expression on myeloma cells that triggers elimination by CD19 CAR-T

T Nerreter, S Letschert, R Götz, S Doose… - Nature …, 2019 - nature.com
Immunotherapy with chimeric antigen receptor-engineered T-cells (CAR-T) is under
investigation in multiple myeloma. There are reports of myeloma remission after CD19 CAR …

Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression

R Bernard, IA Kerman, RC Thompson, EG Jones… - Molecular …, 2011 - nature.com
Several studies have proposed that brain glutamate signaling abnormalities and glial
pathology have a role in the etiology of major depressive disorder (MDD). These …

Selection and validation of a set of reliable reference genes for quantitative sod gene expression analysis in C. elegans

D Hoogewijs, K Houthoofd, F Matthijssens… - BMC molecular …, 2008 - Springer
Abstract Background In the nematode Caenorhabditis elegans the conserved Ins/IGF-1
signaling pathway regulates many biological processes including life span, stress response …