Infectious diseases pose a formidable global challenge, compounded by the emergence of
antimicrobial resistance. Consequently, researchers are actively exploring novel …

An important task of the clinical microbiology laboratory is the performance of antimicrobial
susceptibility testing of significant bacterial isolates. The goals of testing are to detect …

To clarify whether apoptosis is involved in the injury processes induced by autoantibody
against cardiac β1-adrenoceptor, we investigated the biological and apoptotic effects of …

The emergence of vancomycin-intermediate Staphylococcus aureus (VISA) and
heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) over the past …

Abstract (See the article by Patel et al, on pages 969–974.) Background. High rates of
vancomycin failure in methicillin-resistant Staphylococcus aureus (MRSA) infections have …

In the field of orthopaedic surgery, bacterial invasion of implants and the resulting
periprosthetic infections are a common and unresolved problem. Antimicrobial susceptibility …

ABSTRACT A ratio of the vancomycin area under the concentration-time curve to the MIC
(AUC/MIC) of≥ 400 has been associated with clinical success when treating …

Methods Clinical practice guidelines for TDM of VCM were reviewed by a practice guideline
committee that consisted of 18 experts in TDM convened from the JSC and the JSTDM. The …

Abstract (See the article by Kullar et al, on pages 975-981.) Background. We sought to
characterize the pharmacodynamic profile of the more intensive vancomycin dosing …

Individualization of vancomycin dosing based on therapeutic drug monitoring (TDM) data is
known to improve patient outcomes compared with fixed or empirical dosing strategies …