Macromolecules comprise only 2% of vitreous, yet are responsible for its gel state,
transparency, and physiologic function (s) within the eye. Myopia and aging alter collagen …

Patients with diabetes often experience fragile fractures despite normal or higher bone
mineral density (BMD), a phenomenon termed the diabetic bone paradox (DBP). The …

Introduction After injuries, the cartilage healing capacity is limited owing to its nature as a
particular connective tissue without blood vessels, lymphatics, or nerves. The creation of …

Methods UCMSCS were isolated and expanded, and platelet-rich plasma (PRP)
preparations were performed following previously published protocols. PRP was activated …

Nutrition of articular cartilage relies mainly on diffusion and convection of solutes through the
interstitial fluid due to the lack of blood vessels. The diffusion is controlled by two factors …

Investigations into mechanotransduction in connective tissue extracellular matrix (ECM)
have demonstrated that collagen networks show cell-independent mechanosensitive …

Bone is a complex material composite of collagen, an organic protein that makes up much of
mammalian connective tissue, and mineral, the inorganic calcium phosphate that provides …

Nutrition of articular cartilage relies mainly on diffusion and convection of solutes through the
interstitial fluid due to the lack of blood vessels. The diffusion is controlled by two factors …