COVID-19: present and future challenges for dental practice
COVID-19 was declared a pandemic by the World Health Organization, with a high fatality
rate that may reach 8%. The disease is caused by SARS-CoV-2 which is one of the …
rate that may reach 8%. The disease is caused by SARS-CoV-2 which is one of the …
Azithromycin: mechanisms of action and their relevance for clinical applications
Azithromycin is a macrolide antibiotic which inhibits bacterial protein synthesis, quorum-
sensing and reduces the formation of biofilm. Accumulating effectively in cells, particularly …
sensing and reduces the formation of biofilm. Accumulating effectively in cells, particularly …
Pregnancy-associated changes in pharmacokinetics: a systematic review
Background Women are commonly prescribed a variety of medications during pregnancy.
As most organ systems are affected by the substantial anatomical and physiological …
As most organ systems are affected by the substantial anatomical and physiological …
Effects of antibiotics on human microbiota and subsequent disease
KM Keeney, S Yurist-Doutsch… - Annual review of …, 2014 - annualreviews.org
Although antibiotics have significantly improved human health and life expectancy, their
disruption of the existing microbiota has been linked to significant side effects such as …
disruption of the existing microbiota has been linked to significant side effects such as …
Malaria in pregnancy in the Asia-Pacific region
MJ Rijken, R McGready, ME Boel… - The Lancet infectious …, 2012 - thelancet.com
Most pregnant women at risk of for infection with Plasmodium vivax live in the Asia-Pacific
region. However, malaria in pregnancy is not recognised as a priority by many governments …
region. However, malaria in pregnancy is not recognised as a priority by many governments …
Pharmacokinetics and pharmacodynamics of drugs commonly used in pregnancy and parturition
The majority of pregnant women will be treated with a medication other than a vitamin
supplement during their pregnancy. Almost half of these medications will be category C or D …
supplement during their pregnancy. Almost half of these medications will be category C or D …
Pharmacometrics in pregnancy: an unmet need
Pregnant women and their fetuses are orphan populations with respect to the safety and
efficacy of drugs. Physiological and absorption, distribution, metabolism, and excretion …
efficacy of drugs. Physiological and absorption, distribution, metabolism, and excretion …
Eruca sativa seed extract modulates oxidative stress and apoptosis and up-regulates the expression of Bcl-2 and Bax genes in acrylamide-induced testicular …
Acrylamide (ACR) has been previously associated with male sexual dysfunction and
infertility. Eruca sativa (L.)(arugula or rocket) have been widely used in traditional remedies …
infertility. Eruca sativa (L.)(arugula or rocket) have been widely used in traditional remedies …
Sulphadoxine-pyrimethamine plus azithromycin for the prevention of low birthweight in Papua New Guinea: a randomised controlled trial
HW Unger, M Ome-Kaius, RA Wangnapi, AJ Umbers… - BMC medicine, 2015 - Springer
Background Intermittent preventive treatment in pregnancy has not been evaluated outside
of Africa. Low birthweight (LBW,< 2,500 g) is common in Papua New Guinea (PNG) and …
of Africa. Low birthweight (LBW,< 2,500 g) is common in Papua New Guinea (PNG) and …
Use of azithromycin in pregnancy: More doubts than certainties
R Antonucci, L Cuzzolin, C Locci, F Dessole… - Clinical drug …, 2022 - Springer
Macrolides such as azithromycin are commonly prescribed antibiotics during pregnancy.
The good oral bioavailability and transplacental transfer of azithromycin make this drug …
The good oral bioavailability and transplacental transfer of azithromycin make this drug …