The hallmarks of cancer metabolism: Still emerging
Metabolism of cancer cells is geared toward biomass production and proliferation. Since the
metabolic resources within the local tissue are finite, this can lead to nutrient depletion and …
metabolic resources within the local tissue are finite, this can lead to nutrient depletion and …
Polyamines in cancer: integrating organismal metabolism and antitumour immunity
CE Holbert, MT Cullen, RA Casero Jr… - Nature Reviews …, 2022 - nature.com
The natural mammalian polyamines putrescine, spermidine and spermine are essential for
both normal and neoplastic cell function and replication. Dysregulation of metabolism of …
both normal and neoplastic cell function and replication. Dysregulation of metabolism of …
Metabolism of amino acids in cancer
Metabolic reprogramming has been widely recognized as a hallmark of malignancy. The
uptake and metabolism of amino acids are aberrantly upregulated in many cancers that …
uptake and metabolism of amino acids are aberrantly upregulated in many cancers that …
Impact of COVID‐19 pandemic on liver transplantation and alcohol‐associated liver disease in the USA
Involvement of TIGIT in Natural Killer Cell Exhaustion and I... : Hepatology Involvement of
TIGIT in Natural Killer Cell Exhaustion and Immune Escape in Patients and Mouse Model With …
TIGIT in Natural Killer Cell Exhaustion and Immune Escape in Patients and Mouse Model With …
Highly selective urea electrooxidation coupled with efficient hydrogen evolution
Electrochemical urea oxidation offers a sustainable avenue for H2 production and
wastewater denitrification within the water-energy nexus; however, its wide application is …
wastewater denitrification within the water-energy nexus; however, its wide application is …
Bacteria deplete deoxynucleotides to defend against bacteriophage infection
DNA viruses and retroviruses consume large quantities of deoxynucleotides (dNTPs) when
replicating. The human antiviral factor SAMHD1 takes advantage of this vulnerability in the …
replicating. The human antiviral factor SAMHD1 takes advantage of this vulnerability in the …
Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability
Cancer cell metabolism is heavily influenced by microenvironmental factors, including
nutrient availability. Therefore, knowledge of microenvironmental nutrient levels is essential …
nutrient availability. Therefore, knowledge of microenvironmental nutrient levels is essential …
From bench to bed: the tumor immune microenvironment and current immunotherapeutic strategies for hepatocellular carcinoma
Y Fu, S Liu, S Zeng, H Shen - Journal of Experimental & Clinical Cancer …, 2019 - Springer
Hepatocellular carcinoma (HCC) ranks the most common primary liver malignancy and the
third leading cause of tumor-related mortality worldwide. Unfortunately, despite advances in …
third leading cause of tumor-related mortality worldwide. Unfortunately, despite advances in …
Amino acid depletion therapies: starving cancer cells to death
M Butler, LT van der Meer, FN van Leeuwen - Trends in Endocrinology & …, 2021 - cell.com
Targeting tumor cell metabolism is an attractive form of therapy, as it may enhance treatment
response in therapy resistant cancers as well as mitigate treatment-related toxicities by …
response in therapy resistant cancers as well as mitigate treatment-related toxicities by …
Targeting nucleotide metabolism: a promising approach to enhance cancer immunotherapy
H Wu, Y Gong, P Ji, Y **e, YZ Jiang, G Liu - Journal of Hematology & …, 2022 - Springer
Targeting nucleotide metabolism can not only inhibit tumor initiation and progression but
also exert serious side effects. With in-depth studies of nucleotide metabolism, our …
also exert serious side effects. With in-depth studies of nucleotide metabolism, our …