Evolutionary safety of lethal mutagenesis driven by antiviral treatment
Nucleoside analogs are a major class of antiviral drugs. Some act by increasing the viral
mutation rate causing lethal mutagenesis of the virus. Their mutagenic capacity, however …
mutation rate causing lethal mutagenesis of the virus. Their mutagenic capacity, however …
[HTML][HTML] Learning from the COVID-19 pandemic: a systematic review of mathematical vaccine prioritization models
As the world becomes ever more connected, the chance of pandemics increases as well.
The recent COVID-19 pandemic and the concurrent global mass vaccine roll-out provides …
The recent COVID-19 pandemic and the concurrent global mass vaccine roll-out provides …
Differences in Trends in Admissions and Outcomes among Patients from a Secondary Hospital in Madrid during the COVID-19 Pandemic: A Hospital-Based …
R Garcia-Carretero, O Vazquez-Gomez… - Viruses, 2023 - mdpi.com
Spain had some of Europe's highest incidence and mortality rates for coronavirus disease
2019 (COVID-19). This study highlights the impact of the COVID-19 pandemic on daily …
2019 (COVID-19). This study highlights the impact of the COVID-19 pandemic on daily …
Rebound in epidemic control: How misaligned vaccination timing amplifies infection peaks
In this study, we explore the dynamic interplay between the timing of vaccination campaigns
and the trajectory of disease spread in a population. Through modeling and comprehensive …
and the trajectory of disease spread in a population. Through modeling and comprehensive …
Optimal COVID-19 vaccine prioritization by age depends critically on inter-group contacts and vaccination rates
I Atienza-Diez, G Rodriguez-Maroto… - Royal Society …, 2024 - royalsocietypublishing.org
The limited availability of COVID-19 vaccines has prompted extensive research on optimal
vaccination strategies. Previous studies have considered various non-pharmaceutical …
vaccination strategies. Previous studies have considered various non-pharmaceutical …
[HTML][HTML] Impact and Effectiveness of COVID-19 Vaccines Based on Machine Learning Analysis of a Time Series: A Population-Based Study
R Garcia-Carretero, M Ordoñez-Garcia… - Journal of Clinical …, 2024 - mdpi.com
Background: Although confirmed cases of infection with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) have been declining since late 2020 due to general …
coronavirus 2 (SARS-CoV-2) have been declining since late 2020 due to general …
Dynamical systems analysis of a reaction-diffusion SIRS model with optimal control for the COVID-19 spread
We examine an SIRS reaction-diffusion model with local dispersal and spatial heterogeneity
to study COVID-19 dynamics. Using the operator semigroup approach, we establish the …
to study COVID-19 dynamics. Using the operator semigroup approach, we establish the …
Vaccination, asymptomatics and public health information in COVID-19
M Grinfeld, PA Mulheran - Journal of Physics A: Mathematical …, 2024 - iopscience.iop.org
The dynamics of the COVID-19 pandemic is greatly influenced by vaccine quality, as well as
by vaccination rates and the behaviour of infected individuals, both of which reflect public …
by vaccination rates and the behaviour of infected individuals, both of which reflect public …
SIRS Epidemic Models with Delays, Partial and Temporary Immunity and Vaccination
B Chen-Charpentier - AppliedMath, 2024 - mdpi.com
The basic reproduction, or reproductive number, is a useful index that indicates whether or
not there will be an epidemic. However, it is also very important to determine whether an …
not there will be an epidemic. However, it is also very important to determine whether an …
Vaccination strategies impact the probability of outbreak extinction: A case study of COVID-19 transmission
Mass vaccination has proven to be an effective control measure for mitigating the
transmission of infectious diseases. Throughout history, various vaccination strategies have …
transmission of infectious diseases. Throughout history, various vaccination strategies have …