Epigenetics is closely related to cardiovascular diseases. Genome-wide linkage and
association analyses and candidate gene approaches illustrate the multigenic complexity of …

Autophagy is central to the maintenance of organismal homeostasis in both physiological
and pathological situations. Accordingly, alterations in autophagy have been linked to …

Autophagy contributes to the maintenance of intracellular homeostasis in most cells of
cardiovascular origin, including cardiomyocytes, endothelial cells, and arterial smooth …

The onset of heart failure is typically preceded by cardiac hypertrophy, a response of the
heart to increased workload, a cardiac insult such as a heart attack or genetic mutation …

Vascular damage of hypertension has been the focus of hypertension treatment, and
endothelial progenitor cells (EPCs) play an important role in the repair of vascular …

Background/Aims: Reperfusion after an ischaemic insult might cause infarct extension.
Mesenchymal stem cell (MSC)-derived exosomes could attenuate myocardial remodelling in …

Background—The clinical use of doxorubicin is limited by cardiotoxicity. Histopathological
changes include interstitial myocardial fibrosis and the appearance of vacuolated …

ABSTRACT Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce cardiovascular
mortality in patients with diabetes mellitus but the protective mechanism remains elusive …

Modification of histones is one of the important mechanisms of epigenetics, in which genetic
control is determined by factors other than an individual's DNA sequence. Sirtuin family …

A large body of evidence indicates that mitochondrial dysfunction has a major role in the
pathogenesis of multiple cardiovascular disorders. Over the past 2 decades, extraordinary …