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Mitochondria in health, disease, and aging
JS Harrington, SW Ryter, M Plataki… - Physiological …, 2023 - journals.physiology.org
Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …
Mito‐bomb: targeting mitochondria for cancer therapy
X Guo, N Yang, W Ji, H Zhang, X Dong… - Advanced …, 2021 - Wiley Online Library
Cancer has been one of the most common life‐threatening diseases for a long time.
Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) …
Traditional cancer therapies such as surgery, chemotherapy (CT), and radiotherapy (RT) …
Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
Gasdermin D (GSDMD)-activated inflammatory cell death (pyroptosis) causes mitochondrial
damage, but its underlying mechanism and functional consequences are largely unknown …
damage, but its underlying mechanism and functional consequences are largely unknown …
Reactive oxygen species: drivers of physiological and pathological processes
J Checa, JM Aran - Journal of Inflammation research, 2020 - Taylor & Francis
Abstract Since the Great Oxidation Event, about 2.4 billion years ago, the Earth is immersed
in an oxidizing atmosphere. Thus, it has been proposed that excess oxygen, originally a …
in an oxidizing atmosphere. Thus, it has been proposed that excess oxygen, originally a …
History and progress of hypotheses and clinical trials for Alzheimer's disease
PP Liu, Y **e, XY Meng, JS Kang - Signal transduction and targeted …, 2019 - nature.com
Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
memory loss along with neuropsychiatric symptoms and a decline in activities of daily life. Its …
memory loss along with neuropsychiatric symptoms and a decline in activities of daily life. Its …
Mechanisms of biological effects of ionic liquids: from single cells to multicellular organisms
KS Egorova, AV Kibardin, AV Posvyatenko… - Chemical …, 2024 - ACS Publications
The review presents a detailed discussion of the evolving field studying interactions
between ionic liquids (ILs) and biological systems. Originating from molten salt electrolytes …
between ionic liquids (ILs) and biological systems. Originating from molten salt electrolytes …
Piezocatalytic 2D WS2 Nanosheets for Ultrasound‐Triggered and Mitochondria‐Targeted Piezodynamic Cancer Therapy Synergized with Energy Metabolism …
Q Truong Hoang, KA Huynh… - Advanced …, 2023 - Wiley Online Library
Piezoelectric nanomaterials that can generate reactive oxygen species (ROS) by
piezoelectric polarization under an external mechanical force have emerged as an effective …
piezoelectric polarization under an external mechanical force have emerged as an effective …
Mitochondrial regulation of ferroptosis
B Gan - Journal of Cell Biology, 2021 - rupress.org
Ferroptosis is a form of iron-dependent regulated cell death driven by uncontrolled lipid
peroxidation. Mitochondria are double-membrane organelles that have essential roles in …
peroxidation. Mitochondria are double-membrane organelles that have essential roles in …
Mitophagy: an emerging role in aging and age-associated diseases
Mitochondrial dysfunction constitutes one of the hallmarks of aging and is characterized by
irregular mitochondrial morphology, insufficient ATP production, accumulation of …
irregular mitochondrial morphology, insufficient ATP production, accumulation of …
Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles
RQ Yao, C Ren, ZF **a, YM Yao - Autophagy, 2021 - Taylor & Francis
The structural integrity and functional stability of organelles are prerequisites for the viability
and responsiveness of cells. Dysfunction of multiple organelles is critically involved in the …
and responsiveness of cells. Dysfunction of multiple organelles is critically involved in the …