Ultrasound-based micro-/nanosystems for biomedical applications

H Huang, Y Zheng, M Chang, J Song, L **a… - Chemical …, 2024 - ACS Publications
Due to the intrinsic non-invasive nature, cost-effectiveness, high safety, and real-time
capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been …

Organometallic anti-tumor agents: targeting from biomolecules to dynamic bioprocesses

K Peng, Y Zheng, W **a, ZW Mao - Chemical Society Reviews, 2023 - pubs.rsc.org
The great clinical success of cisplatin and its derivatives has convinced people that metal
complexes could play a more significant role in human cancer therapy. However, targeting …

Nanocatalytic theranostics with glutathione depletion and enhanced reactive oxygen species generation for efficient cancer therapy

LH Fu, Y Wan, C Qi, J He, C Li, C Yang, H Xu… - Advanced …, 2021 - Wiley Online Library
Chemodynamic therapy (CDT) is an emerging therapy method that kills cancer cells by
converting intracellular hydrogen peroxide (H2O2) into highly toxic hydroxyl radicals (• OH) …

Synergistic reinforcing of immunogenic cell death and transforming tumor‐associated macrophages via a multifunctional cascade bioreactor for optimizing cancer …

C Huang, B Lin, C Chen, H Wang, X Lin… - Advanced …, 2022 - Wiley Online Library
Immunogenic cell death (ICD) has aroused widespread attention because it can reconstruct
a tumor microenvironment and activate antitumor immunity. This study proposes a two‐way …

Metallo-alginate hydrogel can potentiate microwave tumor ablation for synergistic cancer treatment

Y Zhu, Z Yang, Z Pan, Y Hao, C Wang, Z Dong, Q Li… - Science …, 2022 - science.org
Microwave ablation (MWA) as a local tumor ablation strategy suffers from posttreatment
tumor recurrence. Development of adjuvant biomaterials to potentiate MWA is therefore of …

Photodynamic therapy: Innovative approaches for antibacterial and anticancer treatments

M Kolarikova, B Hosikova, H Dilenko… - Medicinal Research …, 2023 - Wiley Online Library
Photodynamic therapy is an alternative treatment mainly for cancer but also for bacterial
infections. This treatment dates back to 1900 when a German medical school graduate …

Recent advances on modulation of H2O2 in tumor microenvironment for enhanced cancer therapeutic efficacy

Z Chu, J Yang, W Zheng, J Sun, W Wang… - Coordination Chemistry …, 2023 - Elsevier
Due to the rapid proliferation of tumors, the hydrogen peroxide (H 2 O 2) concentration of
tumor cells is higher than that of normal cells, which can be used as an effective target for …

One-step integration of tumor microenvironment-responsive calcium and copper peroxides nanocomposite for enhanced chemodynamic/ion-interference therapy

B Liu, Y Bian, S Liang, M Yuan, S Dong, F He, S Gai… - ACS …, 2021 - ACS Publications
Recently, various metal peroxide nanomaterials have drawn increasing attention as an
efficient hydrogen peroxide (H2O2) self-supplying agent for enhanced tumor therapy …

Biodegradable Ca2+ Nanomodulators Activate Pyroptosis through Mitochondrial Ca2+ Overload for Cancer Immunotherapy

P Zheng, B Ding, G Zhu, C Li, J Lin - Angewandte Chemie, 2022 - Wiley Online Library
Pyroptosis provides a new direction and broad prospects for cancer immunotherapy.
However, the development of a nanoplatform as a pyroptosis inducer is limited, and the …

Ultrasound-augmented mitochondrial calcium ion overload by calcium nanomodulator to induce immunogenic cell death

P Zheng, B Ding, Z Jiang, W Xu, G Li, J Ding… - Nano letters, 2021 - ACS Publications
Immunogenic cell death (ICD), a manner of tumor cell death that can trigger antitumor
immune responses, has received extensive attention as a potential synergistic modality for …