The hippocampal formation in schizophrenia

CA Tamminga, AD Stan… - American Journal of …, 2010 - Am Psychiatric Assoc
The hippocampal formation is one of the most extensively studied regions of the brain, with
well-described anatomy and basic physiology; moreover, aspects of human memory …

GABAergic mechanisms of hippocampal hyperactivity in schizophrenia

S Heckers, C Konradi - Schizophrenia research, 2015 - Elsevier
Schizophrenia is associated with abnormalities of hippocampal structure and function.
Neuroimaging studies have shown that the hippocampus is hyperactive in schizophrenia …

Clinical course of children and adolescents with bipolar spectrum disorders

B Birmaher, D Axelson, M Strober, MK Gill… - Archives of general …, 2006 - jamanetwork.com
Context Despite the high morbidity associated with bipolar disorder (BP), few studies have
prospectively studied the course of this illness in youth. Objective To assess the longitudinal …

Immune activation during pregnancy in mice leads to dopaminergic hyperfunction and cognitive impairment in the offspring: a neurodevelopmental animal model of …

K Ozawa, K Hashimoto, T Kishimoto, E Shimizu… - Biological …, 2006 - Elsevier
BACKGROUND: Maternal viral infection is associated with increased risk for schizophrenia.
It is hypothesized that the maternal immune response to viruses may influence fetal brain …

Resting-state functional network correlates of psychotic symptoms in schizophrenia

A Rotarska-Jagiela, V van de Ven… - Schizophrenia …, 2010 - Elsevier
Schizophrenia has been associated with aberrant intrinsic functional organization of the
brain but the relationship of such deficits to psychopathology is unclear. In this study, we …

The primacy of cognition in schizophrenia.

RW Heinrichs - American Psychologist, 2005 - psycnet.apa.org
Cognitive tasks and concepts are used increasingly in schizophrenia science and treatment.
Recent meta-analyses show that across a spectrum of research domains only cognitive …

Altered resting-state functional connectivity and anatomical connectivity of hippocampus in schizophrenia

Y Zhou, N Shu, Y Liu, M Song, Y Hao, H Liu, C Yu… - Schizophrenia …, 2008 - Elsevier
Hippocampus has been implicated in participating in the pathophysiology of schizophrenia.
However, the functional and anatomical connectivities between hippocampus and other …

Prefrontal activation deficits during episodic memory in schizophrenia

JD Ragland, AR Laird, C Ranganath… - American Journal of …, 2009 - Am Psychiatric Assoc
Objective: Episodic memory impairments represent a core deficit in schizophrenia that
severely limits patients' functional outcome. This quantitative meta-analysis of functional …

Hippocampal pathology in schizophrenia

S Heckers, C Konradi - Behavioral neurobiology of schizophrenia and its …, 2010 - Springer
The hippocampus is abnormal in schizophrenia. Smaller hippocampal volume is the most
consistent finding and is present already in the early stages of the illness. The underlying …

Episodic memory-related activation in schizophrenia: meta-analysis

AM Achim, M Lepage - The British Journal of Psychiatry, 2005 - cambridge.org
BackgroundNumerous studies have examined the neural correlates of episodic memory
deficits in schizophrenia, yielding both consistencies and discrepancies in the reported …