Recent trends in diagnostic biomarkers of tumor microenvironment

P Siminzar, MR Tohidkia, E Eppard, N Vahidfar… - Molecular Imaging and …, 2023 - Springer
The tumor microenvironment (TME) play critical roles in tumor survival, progression, and
metastasis and can be considered potential targets for molecular imaging of cancer. The …

Targeting mitochondria in cancer therapy: insight into photodynamic and photothermal therapies

J Kadkhoda, A Tarighatnia, ND Nader, A Aghanejad - Life Sciences, 2022 - Elsevier
Mitochondria are critical multifunctional organelles in cells that generate power, produce
reactive oxygen species, and regulate cell survival. Mitochondria that are dysfunctional are …

Aptamer-conjugated gold nanoparticles for targeted paclitaxel delivery and photothermal therapy in breast cancer

J Kadkhoda, A Aghanejad, B Safari, J Barar… - Journal of Drug Delivery …, 2022 - Elsevier
The development of novel therapeutic approaches with high efficiency and precision like
photothermal therapy (PTT) is essential to combat breast cancer. The gold nanoparticle …

Osteogenic differentiation of human adipose-derived mesenchymal stem cells in a bisphosphonate-functionalized polycaprolactone/gelatin scaffold

B Safari, M Aghazadeh, A Aghanejad - International Journal of Biological …, 2023 - Elsevier
Recent trends in bone tissue engineering have focused on the development of biomimetic
constructs with appropriate mechanical and physiochemical properties. Here, we report the …

Advances in antibody nanoconjugates for diagnosis and therapy: A review of recent studies and trends

J Kadkhoda, M Akrami-Hasan-Kohal… - International journal of …, 2021 - Elsevier
Nowadays, the targeted imaging probe and drug delivery systems are the novel
breakthrough area in the nanomedicine and treatment of various diseases. Conjugation of …

A review on targeting tumor microenvironment: The main paradigm shift in the mAb-based immunotherapy of solid tumors

A Aghanejad, SF Bonab, M Sepehri… - International journal of …, 2022 - Elsevier
Monoclonal antibodies (mAbs) as biological macromolecules have been remarked the large
and growing pipline of the pharmaceutical market and also the most promising tool in …

Theranostic chimeric antigen receptor (CAR)-T cells: Insight into recent trends and challenges in solid tumors

K Kheyrolahzadeh, MR Tohidkia, A Tarighatnia… - Life Sciences, 2023 - Elsevier
Cell therapy has reached significant milestones in various life-threatening diseases,
including cancer. Cell therapy using fluorescent and radiolabeled chimeric antigen receptor …

Multifunctional magnetic nanoparticles for MRI-guided co-delivery of erlotinib and L-asparaginase to ovarian cancer

S Mohaghegh, A Tarighatnia, Y Omidi… - Journal of …, 2022 - Taylor & Francis
The use of magnetic nanoparticles (MNPs) in biomedical applications has been wildly opted
due to their unique properties. Here, we designed MNPs loaded with erlotinib (ERL/SPION …

Engineering and quantification of bismuth nanoparticles as targeted contrast agent for computed tomography imaging in cellular and animal models

A Tarighatnia, MR Fouladi, MR Tohidkia… - Journal of drug delivery …, 2021 - Elsevier
Abstract Bismuth nanoparticles (Bi-NPs) are developed for use as computed tomography
(CT) contrast agents (CAs). Herein, the dopamine (DOPA) coated Bi-NPs were synthesized …

Mucin-1 conjugated polyamidoamine-based nanoparticles for image-guided delivery of gefitinib to breast cancer

PN Nabi, N Vahidfar, MR Tohidkia, AA Hamidi… - International journal of …, 2021 - Elsevier
PAMAM dendrimers (PAMs) are a group of polymeric macromolecules with distinctive
physicochemical features, which can make them multifunctional theranostic nanoparticles …