Thirty years of resistance: Zig-zag through the plant immune system

BPM Ngou, P Ding, JDG Jones - The Plant Cell, 2022 - academic.oup.com
Understanding the plant immune system is crucial for using genetics to protect crops from
diseases. Plants resist pathogens via a two-tiered innate immune detection-and-response …

NLR receptors in plant immunity: making sense of the alphabet soup

MP Contreras, D Lüdke, H Pai, AA Toghani… - EMBO …, 2023 - embopress.org
Plants coordinately use cell‐surface and intracellular immune receptors to perceive
pathogens and mount an immune response. Intracellular events of pathogen recognition are …

Genome evolution and diversity of wild and cultivated potatoes

D Tang, Y Jia, J Zhang, H Li, L Cheng, P Wang, Z Bao… - Nature, 2022 - nature.com
Potato (Solanum tuberosum L.) is the world's most important non-cereal food crop, and the
vast majority of commercially grown cultivars are highly heterozygous tetraploids. Advances …

Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme

S Ma, D Lapin, LI Liu, Y Sun, W Song, X Zhang… - Science, 2020 - science.org
INTRODUCTION Discrimination of self from nonself is pivotal for cellular organisms, as it
allows the perception of pathogenic invaders that might otherwise multiply unchecked and …

A disease resistance protein triggers oligomerization of its NLR helper into a hexameric resistosome to mediate innate immunity

J Madhuprakash, AA Toghani, MP Contreras… - Science …, 2024 - science.org
NRCs are essential helper NLR (nucleotide-binding domain and leucine-rich repeat)
proteins that execute immune responses triggered by sensor NLRs. The resting state of …

The ectomycorrhizal fungus Pisolithus microcarpus encodes a microRNA involved in cross-kingdom gene silencing during symbiosis

J Wong-Bajracharya, VR Singan… - Proceedings of the …, 2022 - National Acad Sciences
Small RNAs (sRNAs) are known to regulate pathogenic plant–microbe interactions.
Emerging evidence from the study of these model systems suggests that microRNAs …

Sensor NLR immune proteins activate oligomerization of their NRC helpers in response to plant pathogens

MP Contreras, H Pai, Y Tumtas, C Duggan… - The EMBO …, 2023 - embopress.org
Nucleotide‐binding domain leucine‐rich repeat (NLR) immune receptors are important
components of plant and metazoan innate immunity that can function as individual units or …

A potato late blight resistance gene protects against multiple Phytophthora species by recognizing a broadly conserved RXLR-WY effector

X Lin, A Olave-Achury, R Heal, M Pais, K Witek… - Molecular Plant, 2022 - cell.com
Species of the genus Phytophthora, the plant killer, cause disease and reduce yields in
many crop plants. Although many Resistance to Phytophthora infestans (Rpi) genes …

Cell-type-specific responses to fungal infection in plants revealed by single-cell transcriptomics

B Tang, L Feng, MT Hulin, P Ding, W Ma - Cell Host & Microbe, 2023 - cell.com
Pathogen infection is a dynamic process. Here, we employ single-cell transcriptomics to
investigate plant response heterogeneity. By generating an Arabidopsis thaliana leaf atlas …

[HTML][HTML] Plant pathogens convergently evolved to counteract redundant nodes of an NLR immune receptor network

L Derevnina, MP Contreras, H Adachi, J Upson… - PLoS …, 2021 - journals.plos.org
In plants, nucleotide-binding domain and leucine-rich repeat (NLR)-containing proteins can
form receptor networks to confer hypersensitive cell death and innate immunity. One class of …