Monotropein induces autophagy through activation of the NRF2/PINK axis, thereby alleviating sepsis-induced colonic injury

J Qiang, R Yang, X Li, X Xu, M Zhou, X Ji, Y Lu… - International …, 2024 - Elsevier
Sepsis is a systemic inflammatory disease that is caused by a dysregulated host response to
infection and is a life-threatening organ dysfunction that affects many organs, which includes …

Enhanced efficacy of resveratrol-loaded silver nanoparticle in attenuating sepsis-induced acute liver injury: Modulation of inflammation, oxidative stress, and sirt1 …

H Üstündağ, FD Kalindemirtaş, S Doğanay, Ö Demir… - Shock, 2023 - journals.lww.com
Sepsis-induced acute liver injury is a life-threatening condition involving inflammation,
oxidative stress, and endothelial dysfunction. In the present study, the preventive effects of …

Monotropein alleviates septic acute liver injury by restricting oxidative stress, inflammation, and apoptosis via the AKT (Ser473)/GSK3β (Ser9)/Fyn/NRF2 pathway

K **e, F Wang, Y Yang, S Pan, J Wang, N **ao… - International …, 2024 - Elsevier
Sepsis-associated acute liver injury (ALI) is a deadly condition resulting from a systemic
inflammatory response to liver cell damage and malfunction. Monotropein (MON) belongs to …

The role and therapeutic potential of SIRTs in sepsis

J You, Y Li, W Chong - Frontiers in Immunology, 2024 - frontiersin.org
Sepsis is a life-threatening organ dysfunction caused by the host's dysfunctional response to
infection. Abnormal activation of the immune system and disturbance of energy metabolism …

Melatonin: A potential protective multifaceted force for sepsis-induced cardiomyopathy

E Casper, L El Wakeel, N Sabri, R Khorshid, SF Fahmy - Life Sciences, 2024 - Elsevier
Sepsis is a life-threatening condition manifested by organ dysfunction caused by a
dysregulated host response to infection. Lung, brain, liver, kidney, and heart are among the …

Astaxanthin treatment reduces kidney damage and facilitates antioxidant recovery in lithium-intoxicated rats

E Erbaş, H Üstündağ, E Öztürk, SN Parlak, T Atcalı - Toxicon, 2024 - Elsevier
Objective This study aimed to evaluate the protective effects of astaxanthin against lithium-
induced nephrotoxicity, focusing on histopathological changes, oxidative stress modulation …

Investigating the individual and combined effects of coenzyme Q10 and vitamin C on CLP-induced cardiac injury in rats

H Üstündağ, Ö Demir, MT Huyut, N Yüce - Scientific Reports, 2024 - nature.com
Sepsis-induced cardiac injury represents a major clinical challenge, amplifying the urgency
for effective therapeutic interventions. This study aimed to delve into the individual and …

The potential impacts of antioxidant micronutrients on productive and reproductive performances of Mammalian species during stressful conditions

AA Mohammed, S Al-Suwaiegh… - Indian Journal of …, 2024 - indianjournals.com
Background The antioxidant micronutrients supplementation to mammalian species during
stressful condition have gained great attention of nutritionists to alleviate stressful peri …

Therapeutic Effect of Melatonin on CCl4-Induced Fibrotic Liver Model by Modulating Oxidative Stress, Inflammation, and TGF-β1 Signaling Pathway in …

D Cinar, E Altinoz, H Elbe, Y Bicer, D Cetinavci, I Ozturk… - Inflammation, 2024 - Springer
The study aimed to determine the CCl4-induced liver fibrosis model in pinealectomized rats
and biochemically, immunohistochemically, and histopathologically investigate the …

[HTML][HTML] A Biosensor for Simultaneous Detection of Epinephrine and Ascorbic Acid Based on Fe (III)–Polyhistidine-Functionalized Multi-Wall Carbon Nanotube …

B Han, Y Chen, H Wang, J Yan, G Liu, Z Huang… - International Journal of …, 2024 - mdpi.com
Epinephrine (EP) is a very important chemical transmitter in the transmission of nerve
impulses in the central nervous system of mammals. Ascorbic acid (AA) is considered to be …