The present critical review was conducted to evaluate the clinimetric properties of the
Charlson Comorbidity Index (CCI), an assessment tool designed specifically to predict long …

Background A systematic understanding of how multimorbidity has been constructed and
measured is unavailable. This review aimed to examine the definition and measurement of …

Background Treating patients with infections due to multidrug-resistant pathogens often
requires substantial healthcare resources. The purpose of this study was to report estimates …

Health systems rely on commercial prediction algorithms to identify and help patients with
complex health needs. We show that a widely used algorithm, typical of this industry-wide …

Background This study reports estimates of the healthcare costs, length of stay, and mortality
associated with infections due to multidrug-resistant bacteria among elderly individuals in …

Health professionals are encouraged to take the ESC/EACTS Guidelines fully into account
when exercising their clinical judgment, as well as in the determination and the …

Background Frailty is a key determinant of health status and outcomes of health care
interventions in older adults that is not readily measured in Medicare data. This study aimed …

Background: There has been a dramatic shift in use of bariatric procedures, but little is
known about their long-term comparative effectiveness. Objective: To compare weight loss …

Background: Low-dose glucocorticoids are frequently used for the management of
rheumatoid arthritis (RA) and other chronic conditions, but the safety of long-term use …

OBJECTIVE To evaluate the comparative cardiovascular effectiveness and safety of sodium–
glucose cotransporter 2 inhibitors (SGLT-2is), glucagon-like peptide 1 receptor agonists …