Many crystallization processes of great importance, including frost heave, biomineralization,
the synthesis of nanomaterials, and scale formation, occur in small volumes rather than bulk …

New approaches in pharmaceutical chemistry have resulted in more complex drug
molecules in the quest to achieve higher affinity to their targets. However, these 'highly …

A drug's aqueous solubility is defined as the ability to dissolve in a particular solvent, and it
is currently a major hurdle in bringing new drug molecules to the market. According to some …

Introduction: Silica materials, in particular mesoporous silicas, have demonstrated excellent
properties to enhance the oral bioavailability of poorly water-soluble drugs. Current research …

Mesoporous silica nanoparticles (MSNs) displays interesting properties for biomedical
applications such as high chemical stability, large surface area and tunable pores diameters …

Currently, about 40% of approved drugs and nearly 90% of drug candidates are poorly
water-soluble drugs. Low solubility reduces the likelihood that these drugs can be effectively …

Porous materials are ubiquitous and exhibit properties suitable for depositing therapeutic
compounds. Drug loading in porous materials can protect the drug, control its release rate …

The phase behaviors of crystalline solids embedded within nanoporous matrices have been
studied for decades. Classic nucleation theory conjectures that phase stability is determined …

Biominerals typically form within localized volumes, affording organisms great control over
the mineralization process. The influence of such confinement on crystallization is studied …

In this review, available experimental data on the drug confinement in porous matrices via
adsorptive precipitation from supercritical fluid solutions with a special emphasis on the drug …