Tauopathies are classified according to whether tau deposits predominantly contain tau
isoforms with three or four repeats of the microtubule-binding domain. Those in which four …

The differential diagnosis of parkinsonian syndromes is considered one of the most
challenging in neurology and error rates in the clinical diagnosis can be high even at …

Background A Task Force was convened by the EFNS/MDS‐ES Scientist Panel on P
arkinson's disease (PD) and other movement disorders to systemically review relevant …

Two centuries ago in 1817, James Parkinson provided the first medical description of
Parkinson's disease, later refined by Jean-Martin Charcot in the mid-to-late 19th century to …

ABSTRACT PSP is a pathologically defined neurodegenerative tauopathy with a variety of
clinical presentations including typical Richardson's syndrome and other variant PSP …

Parkinson's disease (PD) and atypical Parkinsonian syndromes are progressive
heterogeneous neurodegenerative diseases that share clinical characteristic of …

Background and objectives The last version of the EFNS dementia guidelines is from 2007.
In 2010, the revised guidelines for Alzheimer's disease (AD) were published. The current …

Background Supervised machine learning has been proposed as a revolutionary approach
for identifying sensitive medical image biomarkers (or combination of them) allowing for …

Progressive supranuclear palsy (PSP) is a complex clinicopathologic disease with no
current cure or disease modulating therapies that can only be definitively confirmed at …

Multiple system atrophy (MSA) may be difficult to distinguish clinically from other disorders,
particularly in the early stages of the disease. An autonomic-only presentation can be …