Alternative Fast and Slow Primary Charge‐Separation Pathways in Photosystem II
Photosystem‐II (PSII) is a multi‐subunit protein complex that harvests sunlight to perform
oxygenic photosynthesis. Initial light‐activated charge separation takes place at a reaction …
oxygenic photosynthesis. Initial light‐activated charge separation takes place at a reaction …
Evidence of a Distinctive Enantioselective Binding Mode for the Photoinduced Radical Cyclization of α-Chloroamides in Ene-Reductases
We demonstrate here through molecular simulations and mutational studies the origin of the
enantioselectivity in the photoinduced radical cyclization of α-chloroacetamides catalyzed by …
enantioselectivity in the photoinduced radical cyclization of α-chloroacetamides catalyzed by …
Ultrafast dynamics and catalytic mechanism of fatty acid photodecarboxylase
Fatty acid photodecarboxylase is a newly discovered flavin photoenzyme that converts a
carboxylic acid into a hydrocarbon and a carbon dioxide molecule through decarboxylation …
carboxylic acid into a hydrocarbon and a carbon dioxide molecule through decarboxylation …
Ultrafast photooxidation of protein-bound anionic flavin radicals
B Zhuang, R Ramodiharilafy, U Liebl… - Proceedings of the …, 2022 - National Acad Sciences
The photophysical properties of anionic semireduced flavin radicals are largely unknown
despite their importance in numerous biochemical reactions. Here, we studied the …
despite their importance in numerous biochemical reactions. Here, we studied the …
Tuning proton transfer thermodynamics in SARS-CoV-2 main protease: implications for catalysis and inhibitor design
The catalytic reaction in SARS-CoV-2 main protease is activated by a proton transfer (PT)
from Cys145 to His41. The same PT is likely also required for the covalent binding of some …
from Cys145 to His41. The same PT is likely also required for the covalent binding of some …
Photoinduced hole hop** through tryptophans in proteins
S Záliš, J Heyda, F Šebesta… - Proceedings of the …, 2021 - National Acad Sciences
Hole hop** through tryptophan/tyrosine chains enables rapid unidirectional charge
transport over long distances. We have elucidated structural and dynamical factors …
transport over long distances. We have elucidated structural and dynamical factors …
Characterization of Light-Induced, Short-Lived Interacting Radicals in the Active Site of Flavoprotein Ferredoxin-NADP+ Oxidoreductase
Radicals of flavin adenine dinucleotide (FAD), as well as tyrosine and tryptophan, are widely
involved as key reactive intermediates during electron-transfer (ET) reactions in …
involved as key reactive intermediates during electron-transfer (ET) reactions in …
Contribution Factors of the First Kind Calculated for the Marcus Electron-Transfer Rate and Their Applications
K Mishima, N Kano - The Journal of Physical Chemistry B, 2023 - ACS Publications
In this study, we applied the concept of the “contribution factor of the first kind (CFFK)” to the
original electron-transfer (ET) rate theory proposed by Marcus. Mathematical derivations …
original electron-transfer (ET) rate theory proposed by Marcus. Mathematical derivations …
Effects of nonequilibrium fluctuations on ultrafast short-range electron transfer dynamics
A variety of electron transfer (ET) reactions in biological systems occurs at short distances
and is ultrafast. Many of them show behaviors that deviate from the predictions of the classic …
and is ultrafast. Many of them show behaviors that deviate from the predictions of the classic …
Ultrafast dynamics of nonequilibrium short-range electron transfer in semiquinone flavodoxin
J Yang, Y Zhang, Y Lu, L Wang, F Lu… - The Journal of Physical …, 2022 - ACS Publications
Short-range protein electron transfer (ET) is crucially important in light-induced biological
processes such as in photoenzymes and photoreceptors and often occurs on time scales …
processes such as in photoenzymes and photoreceptors and often occurs on time scales …