The idea of mRNA therapy had been conceived for decades before it came into reality
during the Covid-19 pandemic. The mRNA vaccine emerges as a powerful and general tool …

Myocardial infarction (MI) causes the loss of millions of cardiomyocytes, and current
treatments do not address this root issue. New therapies focus on stimulating cardiomyocyte …

Aims Gene therapies to induce cardiomyocyte (CM) cell cycle re-entry have shown a
potential to treat subacute ischaemic heart failure (IHF) but have not been tested in the more …

Ribonucleic acid (RNA) therapy has been extensively researched for several decades and
has garnered significant attention in recent years owing to its potential in treating a broad …

This review outlines some of the many approaches taken over a decade or more to repair
damaged hearts. We showcase the recent breakthroughs in organ regeneration elicited by …

Introduction: The role of ARRB2 in cardiovascular disease has recently gained increasing
attention. However, the association between ARRB2 polymorphisms and heart failure (HF) …

Cardiac myocytes are responsible for the contraction and relaxation of the myocardium.
Consequently, damage to the myocytes causes systolic and diastolic dysfunctions, which …

Objective Monkeypox virus is now spreading rapidly around the world, but the mechanism of
interaction between it and lupus nephritis is not yet clear. The purpose of this study is to …

The inability of adult mammalian cardiomyocytes (CMs) to undergo cell renewal following
ischemic injury stands as a major impediment to heart function recovery and contributes to …

Therapeutic strategies for the repair of myocardial ischemic damage are an ongoing
challenge for both scientists and clinicians. The obstacle is the limited capacity of the …