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Advances in diagnosis and management of cancer of the esophagus
Esophageal cancer is the seventh most common malignancy worldwide, with over 470 000
new cases diagnosed each year. Two distinct histological subtypes predominate, and …
new cases diagnosed each year. Two distinct histological subtypes predominate, and …
PARP1-targeted fluorescence molecular endoscopy as novel tool for early detection of esophageal dysplasia and adenocarcinoma
S Marcazzan, MJ Braz Carvalho, NT Nguyen… - Journal of Experimental …, 2024 - Springer
Background Esophageal cancer is one of the 10 most common cancers worldwide and its
incidence is dramatically increasing. Despite some improvements, the current surveillance …
incidence is dramatically increasing. Despite some improvements, the current surveillance …
Performance assessment and quality control of fluorescence molecular endoscopy with a multi-parametric rigid standard
A Tenditnaya, RY Gabriëls… - … on Medical Imaging, 2024 - ieeexplore.ieee.org
Fluorescence molecular endoscopy (FME) is emerging as a “red-flag” technique with
potential to deliver earlier, faster, and more personalized detection of disease in the …
potential to deliver earlier, faster, and more personalized detection of disease in the …
Fluorescently labelled vedolizumab to visualise drug distribution and mucosal target cells in inflammatory bowel disease
RY Gabriëls, AM van der Waaij, MD Linssen, M Dobosz… - Gut, 2024 - gut.bmj.com
Objective Improving patient selection and development of biological therapies such as
vedolizumab in IBD requires a thorough understanding of the mechanism of action and …
vedolizumab in IBD requires a thorough understanding of the mechanism of action and …
Improved ex vivo fluorescence imaging of human head and neck cancer using the peptide tracer TPP-IRDye800 targeting membrane-bound Hsp70 on tumor cells
KLK Holzmann, JL Wolf, S Stangl, P Lennartz… - British Journal of …, 2024 - nature.com
Background The primary goal of surgery in HNSCC is the complete resection of tumor cells
with maximum preservation of normal tissue. The membrane Hsp70-targeting fluorescence …
with maximum preservation of normal tissue. The membrane Hsp70-targeting fluorescence …
Detection of tumour-targeted IRDye800CW tracer with commercially available laparoscopic surgical systems
(1) Introduction: Near-infrared fluorescence (NIRF) combined with tumour-targeted tracers,
such as bevacizumab-800CW, could aid surgical decision-making. This study explored the …
such as bevacizumab-800CW, could aid surgical decision-making. This study explored the …
Targeting c-MET for Endoscopic Detection of Dysplastic Lesions within Barrett's Esophagus Using EMI-137 Fluorescence Imaging
Purpose: Esophageal cancer carries a poor prognosis with a 5-year overall survival of less
than 20%. Barrett's esophagus increases the risk of esophageal adenocarcinoma. The aim …
than 20%. Barrett's esophagus increases the risk of esophageal adenocarcinoma. The aim …
Selecting Targets for Molecular Imaging of Gastric Cancer: An Immunohistochemical Evaluation
RD Houvast, M van Duijvenvoorde, K Thijse… - Molecular Diagnosis & …, 2024 - Springer
Purpose Tumor-targeted positron emission tomography (PET) and fluorescence-guided
surgery (FGS) could address current challenges in pre-and intraoperative imaging of gastric …
surgery (FGS) could address current challenges in pre-and intraoperative imaging of gastric …
Effects of Neoadjuvant Therapy on Tumour Target Expression of Oesophageal Cancer Tissue for NIR Fluorescence Imaging
HA Galema, LKA Neijenhuis, LJ Lauwerends… - Molecular Imaging and …, 2024 - Springer
Purpose Oesophaegal cancer patients with a clinical complete response (CR) after
neoadjuvant chemoradiotherapy (nCRT) are candidates for an active surveillance strategy …
neoadjuvant chemoradiotherapy (nCRT) are candidates for an active surveillance strategy …
Selecting Targets for Molecular Imaging of Gastric Cancer
RD Houvast, M van Duijvenvoorde, K Thijse… - 2024 - repository.tudelft.nl
Purpose Tumor-targeted positron emission tomography (PET) and fluorescence-guided
surgery (FGS) could address current challenges in pre-and intraoperative imaging of gastric …
surgery (FGS) could address current challenges in pre-and intraoperative imaging of gastric …