Claudin switching: physiological plasticity of the tight junction
Abstract Tight Junctions (TJs) are multi-molecular complexes in epithelial tissues that
regulate paracellular permeability. Within the TJ complex, claudins proteins span the …
regulate paracellular permeability. Within the TJ complex, claudins proteins span the …
Claudins: vital partners in transcellular and paracellular transport coupling
D Günzel - Pflügers Archiv-European Journal of Physiology, 2017 - Springer
Tight junction (TJ) strands between epithelial or endothelial cells are formed by claudins, a
protein family comprising up to 27 members in mammals. Although many more proteins are …
protein family comprising up to 27 members in mammals. Although many more proteins are …
Non-invasive sensing of transepithelial barrier function and tissue differentiation in organs-on-chips using impedance spectroscopy
Here, we describe methods for combining impedance spectroscopy measurements with
electrical simulation to reveal transepithelial barrier function and tissue structure of human …
electrical simulation to reveal transepithelial barrier function and tissue structure of human …
Epidermal tight junctions in health and disease
JM Brandner, M Zorn-Kruppa, T Yoshida, I Moll… - Tissue …, 2015 - Taylor & Francis
The skin, the largest organ of the body, is an essential barrier that under homeostatic
conditions efficiently protects and/or minimizes damage from both environmental (eg …
conditions efficiently protects and/or minimizes damage from both environmental (eg …
[HTML][HTML] Non-thermal effects of radiofrequency electromagnetic fields
We explored the non-thermal effects of radiofrequency (RF) electromagnetic fields and
established a theoretical framework to elucidate their electrophysiological mechanisms. In …
established a theoretical framework to elucidate their electrophysiological mechanisms. In …
In vitro models of the blood–brain barrier
The blood–brain barrier (BBB) proper is composed of endothelial cells (ECs) of the cerebral
microvasculature, which are interconnected by tight junctions (TJs) that in turn form a …
microvasculature, which are interconnected by tight junctions (TJs) that in turn form a …
Microimpedance tomography system to monitor cell activity and membrane movements in a breathing lung-on-chip
Y Mermoud, M Felder, JD Stucki, AO Stucki… - Sensors and Actuators B …, 2018 - Elsevier
We report about a new microimpedance tomography (MITO) system integrated in a lung-on-
chip that recapitulates the thin alveolar barrier including the cyclic mechanical strain of the …
chip that recapitulates the thin alveolar barrier including the cyclic mechanical strain of the …
Improved cell line IPEC-J2, characterized as a model for porcine jejunal epithelium
SS Zakrzewski, JF Richter, SM Krug, B Jebautzke… - PloS one, 2013 - journals.plos.org
Cell lines matching the source epithelium are indispensable for investigating porcine
intestinal transport and barrier properties on a subcellular or molecular level and …
intestinal transport and barrier properties on a subcellular or molecular level and …
Real-time cellular impedance monitoring and imaging of biological barriers in a dual-flow membrane bioreactor
The generation of physiologically relevant in-vitro models of biological barriers can play a
key role in understanding human diseases and in the development of more predictive …
key role in understanding human diseases and in the development of more predictive …
[HTML][HTML] Targeting the endocannabinoid system with microbial interventions to improve gut integrity
The endocannabinoid system is a metabolic pathway involved in the communication
between the gut microbiota and the host. In the gut, the endocannabinoid system regulates …
between the gut microbiota and the host. In the gut, the endocannabinoid system regulates …