Fluorescent probes for targeting the Golgi apparatus: design strategies and applications
S Xu, KC Yan, ZH Xu, Y Wang, TD James - Chemical Society Reviews, 2024 - pubs.rsc.org
The Golgi apparatus is an essential organelle constructed by the stacking of flattened
vesicles, that is widely distributed in eukaryotic cells and is dynamically regulated during cell …
vesicles, that is widely distributed in eukaryotic cells and is dynamically regulated during cell …
Enzyme-responsive, multi-lock optical probes for molecular imaging and disease theranostics
Optical imaging is an indispensable tool for non-invasive visualization of biomolecules in
living organisms, thereby offering a sensitive approach for disease diagnosis and image …
living organisms, thereby offering a sensitive approach for disease diagnosis and image …
Targeted multicolor in vivo imaging over 1,000 nm enabled by nonamethine cyanines
Recent progress has shown that using wavelengths between 1,000 and 2,000 nm, referred
to as the shortwave-infrared or near-infrared (NIR)-II range, can enable high-resolution in …
to as the shortwave-infrared or near-infrared (NIR)-II range, can enable high-resolution in …
Method to diversify cyanine chromophore functionality enables improved biomolecule tracking and intracellular imaging
Heptamethine indocyanines are invaluable probes for near-infrared (NIR) imaging. Despite
broad use, there are only a few synthetic methods to assemble these molecules, and each …
broad use, there are only a few synthetic methods to assemble these molecules, and each …
NIRII‐HDs: A Versatile Platform for Develo** Activatable NIR‐II Fluorogenic Probes for Reliable In Vivo Analyte Sensing
Z Qin, TB Ren, H Zhou, X Zhang, L He… - Angewandte Chemie …, 2022 - Wiley Online Library
Small‐molecule‐based second near‐infrared (NIR‐II) activatable fluorescent probes can
potentially provide a high target‐to‐background ratio and deep tissue penetration. However …
potentially provide a high target‐to‐background ratio and deep tissue penetration. However …
A general approach to design dual ratiometric fluorescent and photoacoustic probes for quantitatively visualizing tumor hypoxia levels in vivo
S Zhang, H Chen, L Wang, X Qin, BP Jiang… - Angewandte …, 2022 - Wiley Online Library
Herein, we describe an energy balance strategy between fluorescence and photoacoustic
effects by sulfur substitution to transform existing hemicyanine dyes (Cy) into optimized …
effects by sulfur substitution to transform existing hemicyanine dyes (Cy) into optimized …
Heptamethine cyanine dyes with ultra‐efficient excited‐state nonradiative decay for synergistic photothermal immunotherapy
X **a, C Shi, S He, R Wang, Z Zhang… - Advanced Functional …, 2023 - Wiley Online Library
Organic dyes in the excited singlet state (S1) decay via intersystem crossing (ISC) to the
triplet state, radiative dissipation as fluorescence, or nonradiative decay for thermal …
triplet state, radiative dissipation as fluorescence, or nonradiative decay for thermal …
“Dual‐Key‐and‐Lock” NIR‐II NSCyanines Enable High‐Contrast Activatable Phototheranostics in Extrahepatic Diseases
Y Tian, Z Chen, S Liu, F Wu, W Cao… - Angewandte Chemie …, 2023 - Wiley Online Library
Conventional cyanine dyes with a symmetric structure are “always‐on”, which can easily
accumulate in the liver and display high liver background fluorescence, inevitably interfering …
accumulate in the liver and display high liver background fluorescence, inevitably interfering …
Near-infrared fluorescent probes for the detection of cancer-associated proteases
JI Scott, Q Deng, M Vendrell - ACS chemical biology, 2021 - ACS Publications
Proteases are enzymes capable of catalyzing protein breakdown, which is critical across
many biological processes. There are several families of proteases, each of which perform …
many biological processes. There are several families of proteases, each of which perform …
Stimuli-Responsive Macrocyclization Scaffold Allows In Situ Self-Assembly of Radioactive Tracers for Positron Emission Tomography Imaging of Enzyme Activity
J Lin, D Gao, S Wang, G Lv, X Wang, C Lu… - Journal of the …, 2022 - ACS Publications
Target-enabled bioorthogonal reaction and self-assembly of a small-molecule probe into
supramolecules have shown promise for molecular imaging. In this paper, we report a new …
supramolecules have shown promise for molecular imaging. In this paper, we report a new …