Microbiome and human health: current understanding, engineering, and enabling technologies

N Aggarwal, S Kitano, GRY Puah, S Kittelmann… - Chemical …, 2022 - ACS Publications
The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …

Staphylococcus epidermidis and Cutibacterium acnes: Two Major Sentinels of Skin Microbiota and the Influence of Cosmetics

M Fournière, T Latire, D Souak, MGJ Feuilloley… - Microorganisms, 2020 - mdpi.com
Dermatological and cosmetics fields have recently started to focus on the human skin
microbiome and microbiota, since the skin microbiota is involved in the health and dysbiosis …

Propionibacterium acnes and Acne Vulgaris: New Insights from the Integration of Population Genetic, Multi-Omic, Biochemical and Host-Microbe Studies

J McLaughlin, S Watterson, AM Layton, AJ Bjourson… - Microorganisms, 2019 - mdpi.com
The anaerobic bacterium Propionibacterium acnes is believed to play an important role in
the pathophysiology of the common skin disease acne vulgaris. Over the last 10 years our …

From Dysbiosis to Healthy Skin: Major Contributions of Cutibacterium acnes to Skin Homeostasis

M Rozas, A Hart de Ruijter, MJ Fabrega, A Zorgani… - Microorganisms, 2021 - mdpi.com
Cutibacterium acnes is the most abundant bacterium living in human, healthy and sebum-
rich skin sites, such as the face and the back. This bacterium is adapted to this specific …

Exploring the human hair follicle microbiome

MB Lousada, T Lachnit, J Edelkamp… - British Journal of …, 2021 - academic.oup.com
Human hair follicles (HFs) carry complex microbial communities that differ from the skin
surface microbiota. This likely reflects that the HF epithelium differs from the epidermal …

Topical phage therapy in a mouse model of Cutibacterium acnes-induced acne-like lesions

A Rimon, C Rakov, V Lerer, S Sheffer-Levi… - Nature …, 2023 - nature.com
Acne vulgaris is a common neutrophil-driven inflammatory skin disorder in which
Cutibacterium acnes (C. acnes) is known to play a key role. For decades, antibiotics have …

The safety and efficacy of phage therapy for superficial bacterial infections: a systematic review

A Steele, HJ Stacey, S De Soir, JD Jones - Antibiotics, 2020 - mdpi.com
Superficial bacterial infections, such as dermatological, burn wound and chronic
wound/ulcer infections, place great human and financial burdens on health systems globally …

Targeting inflammation in acne: current treatments and future prospects

S Cruz, N Vecerek, N Elbuluk - American journal of clinical dermatology, 2023 - Springer
Acne is a common, chronic inflammatory condition affecting millions of people worldwide,
with significant negative impact on quality of life and mental health. Acne is characterized by …

The anti-inflammatory effects of cannabidiol (CBD) on acne

N Peyravian, S Deo, S Daunert… - Journal of inflammation …, 2022 - Taylor & Francis
Acne is the most common skin condition in the United States and affects approximately 85%
of people ages 12–24. As a multifactorial disease, the pathogenesis of acne involves …

The dynamic balance of the skin microbiome across the lifespan

EC Townsend, LR Kalan - Biochemical Society Transactions, 2023 - portlandpress.com
For decades research has centered on identifying the ideal balanced skin microbiome that
prevents disease and on develo** therapeutics to foster this balance. However, this single …