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Antimicrobial transformation products in the aquatic environment: global occurrence, ecotoxicological risks, and potential of antibiotic resistance
The global spread of antimicrobial resistance (AMR) is concerning for the health of humans,
animals, and the environment in a One Health perspective. Assessments of AMR and …
animals, and the environment in a One Health perspective. Assessments of AMR and …
The time and place for nature in drug discovery
The case for a renewed focus on Nature in drug discovery is reviewed; not in terms of
natural product screening, but how and why biomimetic molecules, especially those …
natural product screening, but how and why biomimetic molecules, especially those …
Low levels of contaminants stimulate harmful algal organisms and enrich their toxins
A widespread increase in intense phytoplankton blooms has been noted in lakes worldwide
since the 1980s, with the summertime peak intensity amplifying in most lakes. Such blooms …
since the 1980s, with the summertime peak intensity amplifying in most lakes. Such blooms …
Metformin contamination in global waters: Biotic and abiotic transformation, byproduct generation and toxicity, and evaluation as a pharmaceutical indicator
Metformin is the first-line antidiabetic drug and one of the most prescribed medications
worldwide. Because of its ubiquitous occurrence in global waters and demonstrated …
worldwide. Because of its ubiquitous occurrence in global waters and demonstrated …
Enrofloxacin induces intestinal microbiota-mediated immunosuppression in zebrafish
W Qiu, T Liu, X Liu, H Chen, S Luo… - … science & technology, 2022 - ACS Publications
The immunosuppressive effects of antibiotics and the potential associations with the
intestinal microbiota of the host have been increasingly recognized in recent years …
intestinal microbiota of the host have been increasingly recognized in recent years …
Distinct efficacies of interlayers in tailoring polyamide nanofiltration membrane performance for organic micropollutant removal: dependent on substrate characteristics
P Cheng, Y Liu, X Wei, K Fan, S **a - Environmental Science & …, 2024 - ACS Publications
Interlayered thin-film nanocomposite (TFN) membranes have shown the potential to boost
nanofiltration performance for water treatment applications including the removal of organic …
nanofiltration performance for water treatment applications including the removal of organic …
Exploring outputs of the intergovernmental science-policy panel on chemicals, waste, and pollution prevention
The Science-Policy Panel (SPP) on Chemicals, Waste, and Pollution Prevention, now being
established under a mandate of the United Nations Environment Assembly, will address …
established under a mandate of the United Nations Environment Assembly, will address …
Biological-activity-based prioritization of antidepressants in wastewater in England and Japan
H Zhang, D Kato, MO Ihara, MD Jürgens… - Environmental …, 2023 - ACS Publications
Antidepressants are one of the most commonly prescribed pharmaceuticals. Although they
have been frequently detected in aquatic environments around the globe, little is known …
have been frequently detected in aquatic environments around the globe, little is known …
Human apparent volume of distribution predicts bioaccumulation of ionizable organic chemicals in zebrafish embryos
Chemicals with elevated bioaccumulation profiles present potential hazards to public health
and the environment. Ionizable organic compounds (IOCs) increasingly represent a large …
and the environment. Ionizable organic compounds (IOCs) increasingly represent a large …
Transcriptome-Guided Characterization of the Environmental Toxicity of Metformin: Disruption of Energy Homeostasis and Inhibition of Embryonic Development of …
Z Zhang, H Shi, K Zhang, R An, C Wang… - Environmental …, 2024 - ACS Publications
Metformin has been widely detected in aquatic ecosystems, yet the knowledge of its impact
on aquatic organisms, particularly at environmentally relevant concentrations, remains …
on aquatic organisms, particularly at environmentally relevant concentrations, remains …