Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

The biosynthesis of antibiotics and self-protection mechanisms employed by antibiotic
producers are an integral part of the growing antibiotic resistance threat. The origins of …

Ribosomally synthesized and post‐translationally modified peptides (RiPPs) are a
fascinating group of natural products that exhibit diverse structural features and bioactivities …

Tetracyclines have been foundational antibacterial agents for more than 70 years. Renewed
interest in tetracycline antibiotics is being driven by advancements in tetracycline synthesis …

Abstract In the One Health context, wastewater treatment plants (WWTPs) are central to
safeguarding water resources. Nonetheless, many questions remain about their …

The worldwide prevalence of infections caused by antibiotic-resistant Gram-negative
bacteria poses a serious threat to public health due to the limited therapeutic alternatives …

Overuse of broad-spectrum antibiotics to control human and plant pathogens greatly
accelerated the development of antibiotic resistance among bacteria and fungi. Therefore …

The human gut bacterial genotoxin colibactin is a possible key driver of colorectal cancer
(CRC) development. Understanding colibactin's biological effects remains difficult owing to …

Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a class of
cyclic or linear peptidic natural products with remarkable structural and functional diversity …

Polymyxins are cationic antimicrobial peptides used as the last-line therapy to treat
multidrug-resistant Gram-negative bacterial infections. The bactericidal activity of polymyxins …