Pathophysiology of decompensated cirrhosis: portal hypertension, circulatory dysfunction, inflammation, metabolism and mitochondrial dysfunction

C Engelmann, J Clària, G Szabo, J Bosch… - Journal of …, 2021 - Elsevier
Patients with acutely decompensated cirrhosis have a dismal prognosis and frequently
progress to acute-on-chronic liver failure, which is characterised by hepatic and extrahepatic …

Infections in patients with cirrhosis increase mortality four-fold and should be used in determining prognosis

V Arvaniti, G D'Amico, G Fede, P Manousou… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS:: A staged prognostic model of cirrhosis based on varices, ascites,
and bleeding has been proposed. We analyzed data on infections in patients with cirrhosis …

EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis

P Angeli, M Bernardi, C Villanueva, C Francoz… - Journal of …, 2018 - Elsevier
The natural history of cirrhosis is characterised by an asymptomatic compensated phase
followed by a decompensated phase, marked by the development of overt clinical signs, the …

[PDF][PDF] Management of adult patients with ascites due to cirrhosis: an update

BA Runyon - Hepatology, 2009 - Wiley Online Library
A Medline search from 1966 through 2007 was performed; search terms included ascites,
hepatorenal syndrome, diet therapy, drug therapy, radiotherapy, surgery, and therapy. The …

The pathophysiology of arterial vasodilatation and hyperdynamic circulation in cirrhosis

S Møller, F Bendtsen - Liver International, 2018 - Wiley Online Library
Patients with cirrhosis and portal hypertension often develop complications from a variety of
organ systems leading to a multiple organ failure. The combination of liver failure and portal …

[PDF][PDF] Management of adult patients with ascites due to cirrhosis

BA Runyon - Hepatology, 2004 - Wiley Online Library
Background Cirrhosis was the tenth leading cause of death in the United States, according
to a 2000 Vital Statistics Report, in which data was collected through 1998. 4 Ascites is the …

Cirrhotic cardiomyopathy

EM Zardi, A Abbate, DM Zardi, A Dobrina… - Journal of the American …, 2010 - jacc.org
Cirrhotic cardiomyopathy is a clinical syndrome in patients with liver cirrhosis characterized
by an abnormal and blunted response to physiologic, pathologic, or pharmacologic stress …

Cirrhotic cardiomyopathy: pathogenesis and clinical relevance

S Wiese, JD Hove, F Bendtsen, S Møller - … reviews Gastroenterology & …, 2014 - nature.com
Cirrhosis is known to cause alterations in the systemic haemodynamic system. Cirrhotic
cardiomyopathy designates a cardiac dysfunction that includes impaired cardiac contractility …

[PDF][PDF] Circulatory function and hepatorenal syndrome in cirrhosis

L Ruiz‐del‐Arbol, A Monescillo, C Arocena… - …, 2005 - Wiley Online Library
The pathogenic mechanism of hepatorenal syndrome is not well established. We
investigated the circulatory function in cirrhosis before and after the development of …

Cardiovascular complications of cirrhosis

S Møller, JH Henriksen - Postgraduate medical journal, 2009 - academic.oup.com
Cardiovascular complications of cirrhosis include cardiac dysfunction and abnormalities in
the central, splanchnic and peripheral circulation, and haemodynamic changes caused by …