Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome

R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …

Diagnosis and management of obstructive sleep apnea: a review

DJ Gottlieb, NM Punjabi - Jama, 2020 - jamanetwork.com
Importance Obstructive sleep apnea (OSA) affects 17% of women and 34% of men in the US
and has a similar prevalence in other countries. This review provides an update on the …

American Association of Clinical Endocrinology clinical practice guideline: develo** a diabetes mellitus comprehensive care plan—2022 update

L Blonde, GE Umpierrez, SS Reddy, JB McGill… - Endocrine Practice, 2022 - Elsevier
Objective The objective of this clinical practice guideline is to provide updated and new
evidence-based recommendations for the comprehensive care of persons with diabetes …

Semaglutide 2· 4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled …

M Davies, L Færch, OK Jeppesen, A Pakseresht… - The Lancet, 2021 - thelancet.com
Background This trial assessed the efficacy and safety of the GLP-1 analogue once a week
subcutaneous semaglutide 2· 4 mg versus semaglutide 1· 0 mg (the dose approved for …

Obesity as a multisystem disease: Trends in obesity rates and obesity‐related complications

S Sarma, S Sockalingam, S Dash - Diabetes, Obesity and …, 2021 - Wiley Online Library
Obesity is a chronic multisystem disease associated with increased morbidity and mortality.
The increasing prevalence of obesity makes it a major healthcare challenge across both …

Obstructive sleep apnea in cardiovascular disease: a review of the literature and proposed multidisciplinary clinical management strategy

JR Tietjens, D Claman, EJ Kezirian… - Journal of the …, 2019 - Am Heart Assoc
Cardiovascular disease (CVD) remains a highly prevalent cause of morbidity and mortality,
both in the United States and worldwide. In parallel with the development of new and …

Sleep duration and quality: impact on lifestyle behaviors and cardiometabolic health: a scientific statement from the American Heart Association

MP St-Onge, MA Grandner, D Brown, MB Conroy… - Circulation, 2016 - Am Heart Assoc
Sleep is increasingly recognized as an important lifestyle contributor to health. However, this
has not always been the case, and an increasing number of Americans choose to curtail …

Obesity and type 2 diabetes: two diseases with a need for combined treatment strategies-EASO can lead the way

DR Leitner, G Frühbeck, V Yumuk, K Schindler, D Micic… - Obesity facts, 2017 - karger.com
Obesity is a chronic metabolic disease affecting adults and children worldwide. It has
become one of the leading causes of death, as obesity is known to be the main risk factor for …

American Association of Clinical Endocrinologists and American College of Endocrinology comprehensive clinical practice guidelines for medical care of patients with …

WT Garvey, JI Mechanick, EM Brett, AJ Garber… - Endocrine Practice, 2016 - Elsevier
Objective Development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and the American College of …

Weight loss and improvement in comorbidity: differences at 5%, 10%, 15%, and over

DH Ryan, SR Yockey - Current obesity reports, 2017 - Springer
Abstract Purpose of Review One begins to see improvement in glycemic measures and
triglycerides with small amounts of weight loss, but with greater levels of weight loss there is …