Abstract The Glasgow Outcome Scale (GOS) was first published in 1975 by Bryan Jennett
and Michael Bond. With over 4,000 citations to the original paper, it is the most highly cited …

Background Severe trauma represents a major global public health burden and the
management of post-traumatic bleeding continues to challenge healthcare systems around …

Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

Background Severe trauma continues to represent a global public health issue and mortality
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …

Severe traumatic brain injury remains a major health-care problem worldwide. Although
major progress has been made in understanding of the pathophysiology of this injury, this …

Abstract The latest French Guidelines for the management in the first 24 hours of patients
with severe traumatic brain injury (TBI) were published in 1998. Due to recent changes …

Background Erythropoietin might have neurocytoprotective effects. In this trial, we studied its
effect on neurological recovery, mortality, and venous thrombotic events in patients with …

Importance The Fragility Index (FI) is the minimum number of participants in a randomized
clinical trial (RCT) whose status would have to change from a nonevent (not experiencing …

Objective: To assess comparative benefits and harms across three airway management
approaches (bag valve mask [BVM], supraglottic airway [SGA], and endotracheal intubation …

Importance Current prehospital traumatic brain injury guidelines use a systolic blood
pressure threshold of less than 90 mm Hg for treating hypotension for individuals 10 years …