Background A dysregulated stress response, including exaggerated affective reactivity and
abnormal hypothalamic-pituitary-adrenal axis responsivity, has been implicated in the …

Establishing the biological signatures of human emotions, thoughts, and behavior has long
been the holy grail of neuroscience research. Advancements in brain imaging and …

Background Neurocognitive factors including aberrant reward learning, blunted GABA
(gamma-aminobutyric acid), and potentiated stress sensitivity have been linked to …

This issue of the Journal is primarily focused on affective disorders while also addressing
the use of pharmacogenomics in the treatment of psychiatric disorders and speaking to …